000048127 001__ 48127 000048127 005__ 20190131090519.0 000048127 0247_ $$2doi$$a10.1186/s12917-014-0206-7 000048127 0248_ $$2sideral$$a87955 000048127 037__ $$aART-2014-87955 000048127 041__ $$aeng 000048127 100__ $$aIsidoro-Ayza, M. 000048127 245__ $$aBrucella ceti infection in dolphins from the Western Mediterranean sea 000048127 260__ $$c2014 000048127 5060_ $$aAccess copy available to the general public$$fUnrestricted 000048127 5203_ $$aBackground: Brucella ceti infections have been increasingly reported in cetaceans. Brucellosis in these animals is associated with meningoencephalitis, abortion, discospondylitis’, subcutaneous abscesses, endometritis and other pathological conditions B. ceti infections have been frequently described in dolphins from both, the Atlantic and Pacific Oceans. In the Mediterranean Sea, only two reports have been made: one from the Italian Tyrrhenian Sea and the other from the Adriatic Sea. Results: We describe the clinical and pathological features of three cases of B. ceti infections in three dolphins stranded in the Mediterranean Catalonian coast. One striped dolphin had neurobrucellosis, showing lethargy, incoordination and lateral swimming due to meningoencephalitis, A B. ceti infected bottlenose dolphin had discospondylitis, and another striped dolphin did not show clinical signs or lesions related to Brucella infection. A detailed characterization of the three B. ceti isolates was performed by bacteriological, molecular, protein and fatty acid analyses. Conclusions: All the B. ceti strains originating from Mediterranean dolphins cluster together in a distinct phylogenetic clade, close to that formed by B. ceti isolates from dolphins inhabiting the Atlantic Ocean. Our study confirms the severity of pathological signs in stranded dolphins and the relevance of B. ceti as a pathogen in the Mediterranean Sea. 000048127 536__ $$9info:eu-repo/grantAgreement/ES/DGA/A14$$9info:eu-repo/grantAgreement/ES/MICINN/AGL2011-30453-C04 000048127 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000048127 590__ $$a1.777$$b2014 000048127 591__ $$aVETERINARY SCIENCES$$b21 / 133 = 0.158$$c2014$$dQ1$$eT1 000048127 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000048127 700__ $$aRuiz-Villalobos, N. 000048127 700__ $$aPérez, L. 000048127 700__ $$aGuzmán-Verri, C. 000048127 700__ $$aMuñoz, P.M.$$uUniversidad de Zaragoza 000048127 700__ $$aAlegre, F. 000048127 700__ $$0(orcid)0000-0002-5225-661X$$aBarberán, M.$$uUniversidad de Zaragoza 000048127 700__ $$aChacón-Díaz, C. 000048127 700__ $$aChaves-Olarte, E. 000048127 700__ $$aGonzález-Barrientos, R. 000048127 700__ $$aMoreno, E. 000048127 700__ $$aBlasco, J.M. 000048127 700__ $$aDomingo, M. 000048127 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería 000048127 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal 000048127 773__ $$g10, 1 (2014), 206 [10 pp.]$$pBMC Vet. Res.$$tBMC VETERINARY RESEARCH$$x1746-6148 000048127 8564_ $$s2471304$$uhttps://zaguan.unizar.es/record/48127/files/texto_completo.pdf$$yVersión publicada 000048127 8564_ $$s106089$$uhttps://zaguan.unizar.es/record/48127/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000048127 909CO $$ooai:zaguan.unizar.es:48127$$particulos$$pdriver 000048127 951__ $$a2019-01-31-08:54:48 000048127 980__ $$aARTICLE