000048158 001__ 48158
000048158 005__ 20170504095947.0
000048158 0247_ $$2doi$$a10.1038/srep04913
000048158 0248_ $$2sideral$$a86874
000048158 037__ $$aART-2014-86874
000048158 041__ $$aeng
000048158 100__ $$0(orcid)0000-0003-2685-5739$$aNerin, C.$$uUniversidad de Zaragoza
000048158 245__ $$aCompounds from multilayer plastic bags cause reproductive failures in artificial insemination
000048158 260__ $$c2014
000048158 5060_ $$aAccess copy available to the general public$$fUnrestricted
000048158 5203_ $$aHigh levels of reproductive failure were detected in some Spanish sow farms in the Spring of 2010. Regular returns to estrus and variable reductions in litter size were observed. The problem started suddenly and did not appear to be related to the quality of the ejaculates, disease, alterations of body condition or any other apparent reasons. Subsequent studies determined that the problem was the origin of the plastic bags used for semen storage. Chemical analysis of the suspicious bags identified unexpected compounds such as BADGE, a cyclic lactone and an unknown phthalate that leached into the semen at concentrations of 0.2 to 2.5 mg/L. Spermatozoa preserved in these bags passed all of the routine quality control tests, and no differences were observed between storage in the control and suspicious bags (p . 0.05). In vitro fecundation tests and endocrine profiler panel analysis (EPP) did not show any alterations, whereas the in vivo tests confirmed the described failure. This is the first described relationship between reproductive failure and toxic compounds released from plastic bags.
000048158 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000048158 590__ $$a5.578$$b2014
000048158 591__ $$aMULTIDISCIPLINARY SCIENCES$$b5 / 57 = 0.088$$c2014$$dQ1$$eT1
000048158 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000048158 700__ $$aUbeda, J.L.
000048158 700__ $$0(orcid)0000-0002-3703-7902$$aAlfaro, P.
000048158 700__ $$aDahmani, Y.
000048158 700__ $$0(orcid)0000-0002-0759-9170$$aAznar, M.$$uUniversidad de Zaragoza
000048158 700__ $$0(orcid)0000-0003-2638-9221$$aCanellas, E.
000048158 700__ $$aAusejo, R.
000048158 7102_ $$12009$$2750$$aUniversidad de Zaragoza$$bDepartamento de Química Analítica$$cQuímica Analítica
000048158 773__ $$g4 (2014), 4913 [10 pp.]$$pSci. rep.$$tSCIENTIFIC REPORTS$$x2045-2322
000048158 8564_ $$s614405$$uhttps://zaguan.unizar.es/record/48158/files/texto_completo.pdf$$yVersión publicada
000048158 8564_ $$s101526$$uhttps://zaguan.unizar.es/record/48158/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000048158 909CO $$ooai:zaguan.unizar.es:48158$$particulos$$pdriver
000048158 951__ $$a2017-05-04-09:53:09
000048158 980__ $$aARTICLE