doi:10.5232/ricyde2015.04101engGaratachea-Vallejo, N.Santiago, C.Yvert, T.Verde-Rello, Z.Fiuza-Luces, C.Santos-Lozano, A.Gómez-Gallego, F.Lucía, A.Genetic variants in the PPARD-PPARGC1A-NRF-TFAM mitochondriogenesis pathway are neither associated with muscle characteristics nor physical performance in elderlyART-2015-91433We studied the influence of genetic polymorphisms involved in the PPARD-PPARGC1A-NRF-TFAM mitochondriogenesis pathway (rs6949152, rs12594956, rs2267668, rs8192678, and rs1937) on muscle phenotypes (thigh muscles’ cross-sectional, maximal handgrip-strength and 30-second chair stand-test) and Barthel index in Caucasian (Spanish) community-dwelling old people (n=75, 21 men, 54 women; 71–94 years). We found no significant genetic associations with the studied phenotypes. Multiple, com- plex gene-environment and gene-gene interactions which are yet to be determined are likely to play a more determinant role.2015http://zaguan.unizar.es/record/4816110.5232/ricyde2015.04101http://zaguan.unizar.es/record/48161oai:zaguan.unizar.es:48161info:eu-repo/grantAgreement/ES/MINECO/FIS/PI09-00194Revista internacional de ciencias del deporte 11, 41 (2015), 196-208by-nc-ndhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccess