48684 20200221144248.0 doi 10.1038/srep23622 sideral 94673 ART-2016-94673 eng (orcid)0000-0002-1184-5901 Lozano, A. Control strategies of 3-cell Central Pattern Generator via global stimuli 2016 Access copy available to the general public Unrestricted The study of the synchronization patterns of small neuron networks that control several biological processes has become an interesting growing discipline. Some of these synchronization patterns of individual neurons are related to some undesirable neurological diseases, and they are believed to play a crucial role in the emergence of pathological rhythmic brain activity in different diseases, like Parkinson''s disease. We show how, with a suitable combination of short and weak global inhibitory and excitatory stimuli over the whole network, we can switch between different stable bursting patterns in small neuron networks (in our case a 3-neuron network). We develop a systematic study showing and explaining the effects of applying the pulses at different moments. Moreover, we compare the technique on a completely symmetric network and on a slightly perturbed one (a much more realistic situation). The present approach of using global stimuli may allow to avoid undesirable synchronization patterns with nonaggressive stimuli. info:eu-repo/grantAgreement/ES/UZ/CUD2015-CIE-05 info:eu-repo/grantAgreement/ES/MICINN/MTM2015-64095-P info:eu-repo/grantAgreement/ES/MICINN/MTM2013-46337-C2-2-P info:eu-repo/grantAgreement/ES/MICINN/MTM2012-31883 info:eu-repo/grantAgreement/ES/DGA/E48 info:eu-repo/grantAgreement/ES/DGA/E15 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 4.259 2016 MULTIDISCIPLINARY SCIENCES 10 / 63 = 0.159 2016 Q1 T1 1.691 2016 Multidisciplinary 2016 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion (orcid)0000-0003-3426-105X Rodriguez, M. (orcid)0000-0002-8089-343X Barrio, R. Universidad de Zaragoza 2005 595 Universidad de Zaragoza Dpto. Matemática Aplicada Área Matemática Aplicada 6 (2016), 23622 [10 pp] Sci. rep. SCIENTIFIC REPORTS 2045-2322 3798618 http://zaguan.unizar.es/record/48684/files/texto_completo.pdf Versión publicada 114550 http://zaguan.unizar.es/record/48684/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:48684 articulos driver 2020-02-21-13:26:32 ARTICLE