000048706 001__ 48706 000048706 005__ 20200221144248.0 000048706 0247_ $$2doi$$a10.3762/bjoc.12.50 000048706 0248_ $$2sideral$$a94753 000048706 037__ $$aART-2016-94753 000048706 041__ $$aeng 000048706 100__ $$0(orcid)0000-0001-9988-0287$$aGiménez Sonsona, I. 000048706 245__ $$aThe aminoindanol core as a key scaffold in bifunctional organocatalysts 000048706 260__ $$c2016 000048706 5060_ $$aAccess copy available to the general public$$fUnrestricted 000048706 5203_ $$aThe 1,2-aminoindanol scaffold has been found to be very efficient, enhancing the enantioselectivity when present in organocatalysts. This may be explained by its ability to induce a bifunctional activation of the substrates involved in the reaction. Thus, it is easy to find hydrogen-bonding organocatalysts ((thio)ureas, squaramides, quinolinium thioamide, etc.) in the literature containing this favored structural core. They have been successfully employed in reactions such as Friedel-Crafts alkylation, Michael addition, Diels-Alder and aza-Henry reactions. However, the 1,2-aminoindanol core incorporated into proline derivatives has been scarcely explored. Herein, the most representative and illustrative examples are compiled and this review will be mainly focused on the cases where the aminoindanol moiety confers bifunctionality to the organocatalysts. 000048706 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E104$$9info:eu-repo/grantAgreement/ES/MICINN/CTQ2013-44367-C2-1-P$$9info:eu-repo/grantAgreement/ES/UZ/JIUZ-2014-CIE-07 000048706 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000048706 590__ $$a2.337$$b2016 000048706 591__ $$aCHEMISTRY, ORGANIC$$b25 / 59 = 0.424$$c2016$$dQ2$$eT2 000048706 592__ $$a1.02$$b2016 000048706 593__ $$aOrganic Chemistry$$c2016$$dQ1 000048706 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000048706 700__ $$0(orcid)0000-0001-6832-8983$$aMarqués-López, E.$$uUniversidad de Zaragoza 000048706 700__ $$0(orcid)0000-0002-5244-9569$$aHerrera, R.P.$$uUniversidad de Zaragoza 000048706 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica 000048706 773__ $$g12 (2016), 505-523$$pBeilstein J. Org. Chem.$$tBEILSTEIN JOURNAL OF ORGANIC CHEMISTRY$$x1860-5397 000048706 8564_ $$s1279373$$uhttps://zaguan.unizar.es/record/48706/files/texto_completo.pdf$$yVersión publicada 000048706 8564_ $$s75179$$uhttps://zaguan.unizar.es/record/48706/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000048706 909CO $$ooai:zaguan.unizar.es:48706$$particulos$$pdriver 000048706 951__ $$a2020-02-21-13:26:39 000048706 980__ $$aARTICLE