000056112 001__ 56112 000056112 005__ 20200221144252.0 000056112 0247_ $$2doi$$a10.1093/europace/euv405 000056112 0248_ $$2sideral$$a95180 000056112 037__ $$aART-2016-95180 000056112 041__ $$aeng 000056112 100__ $$aBaumert, Mathias 000056112 245__ $$aQT interval variability in body surface ECG: measurement, physiological basis, and clinical value: position statement and consensus guidance endorsed by the European Heart Rhythm Association jointly with the ESCWorking Group on Cardiac Cellular Electrophysiology 000056112 260__ $$c2016 000056112 5060_ $$aAccess copy available to the general public$$fUnrestricted 000056112 5203_ $$aThis consensus guideline discusses the electrocardiographic phenomenon of beat-to-beat QT interval variability (QTV) on surface electrocardiograms. The text covers measurement principles, physiological basis, and clinical value of QTV. Technical considerations include QT interval measurement and the relation between QTV and heart rate variability. Research frontiers of QTV include understanding of QTV physiology, systematic evaluation of the link between QTV and direct measures of neural activity, modelling of the QTV dependence on the variability of other physiological variables, distinction between QTV and general T wave shape variability, and assessing of the QTV utility for guiding therapy. Increased QTV appears to be a risk marker of arrhythmic and cardiovascular death. It remains to be established whether it can guide therapy alone or in combination with other risk factors. QT interval variability has a possible role in non-invasive assessment of tonic sympathetic activity. 000056112 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000056112 590__ $$a4.53$$b2016 000056112 591__ $$aCARDIAC & CARDIOVASCULAR SYSTEMS$$b31 / 126 = 0.246$$c2016$$dQ1$$eT1 000056112 592__ $$a2.673$$b2016 000056112 593__ $$aPhysiology (medical)$$c2016$$dQ1 000056112 593__ $$aCardiology and Cardiovascular Medicine$$c2016$$dQ1 000056112 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000056112 700__ $$aPorta, Alberto 000056112 700__ $$aVos, Marc A. 000056112 700__ $$aMalik, Marek 000056112 700__ $$aCouderc, Jean-Philippe 000056112 700__ $$0(orcid)0000-0003-3434-9254$$aLaguna, Pablo$$uUniversidad de Zaragoza 000056112 700__ $$aPiccirillo, Gianfranco 000056112 700__ $$aSmith, Godfrey L. 000056112 700__ $$aTereshchenko, Larisa G. 000056112 700__ $$aVolders, Paul G.A. 000056112 7102_ $$15008$$2800$$aUniversidad de Zaragoza$$bDpto. Ingeniería Electrón.Com.$$cÁrea Teoría Señal y Comunicac. 000056112 773__ $$g(2016), 2-20$$pEuropace$$tEUROPACE$$x1099-5129 000056112 8564_ $$s871368$$uhttps://zaguan.unizar.es/record/56112/files/texto_completo.pdf$$yVersión publicada 000056112 8564_ $$s106520$$uhttps://zaguan.unizar.es/record/56112/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000056112 909CO $$ooai:zaguan.unizar.es:56112$$particulos$$pdriver 000056112 951__ $$a2020-02-21-13:28:06 000056112 980__ $$aARTICLE