000056818 001__ 56818
000056818 005__ 20200221144255.0
000056818 0247_ $$2doi$$a10.1186/s13071-016-1803-z
000056818 0248_ $$2sideral$$a96283
000056818 037__ $$aART-2016-96283
000056818 041__ $$aeng
000056818 100__ $$0(orcid)0000-0001-7483-046X$$aEstrada-Peña, A.$$uUniversidad de Zaragoza
000056818 245__ $$aNested coevolutionary networks shape the ecological relationships of ticks, hosts, and the Lyme disease bacteria of the Borrelia burgdorferi (s.l.) complex
000056818 260__ $$c2016
000056818 5060_ $$aAccess copy available to the general public$$fUnrestricted
000056818 5203_ $$aBackground: The bacteria of the Borrelia burgdorferi (s.l.) (BBG) complex constitute a group of tick-transmitted pathogens that are linked to many vertebrate and tick species. The ecological relationships between the pathogens, the ticks and the vertebrate carriers have not been analysed. The aim of this study was to quantitatively analyse these interactions by creating a network based on a large dataset of associations. Specifically, we examined the relative positions of partners in the network, the phylogenetic diversity of the tick''s hosts and its impact on BBG circulation. The secondary aim was to evaluate the segregation of BBG strains in different vectors and reservoirs. Results: BBG circulates through a nested recursive network of ticks and vertebrates that delineate closed clusters. Each cluster contains generalist ticks with high values of centrality as well as specialist ticks that originate nested sub-networks and that link secondary vertebrates to the cluster. These results highlighted the importance of host phylogenetic diversity for ticks in the circulation of BBG, as this diversity was correlated with high centrality values for the ticks. The ticks and BBG species in each cluster were not significantly associated with specific branches of the phylogeny of host genera (R 2 = 0.156, P = 0.784 for BBG; R 2 = 0.299, P = 0.699 for ticks). A few host genera had higher centrality values and thus higher importance for BBG circulation. However, the combined contribution of hosts with low centrality values could maintain active BBG foci. The results suggested that ticks do not share strains of BBG, which were highly segregated among sympatric species of ticks. Conclusions: We conclude that BBG circulation is supported by a highly redundant network. This network includes ticks with high centrality values and high host phylogenetic diversity as well as ticks with low centrality values. This promotes ecological sub-networks and reflects the high resilience of BBG circulation. The functional redundancy in BBG circulation reduces disturbances due to the removal of vertebrates as it allows ticks to fill other biotic niches.
000056818 536__ $$9info:eu-repo/grantAgreement/EUR/COST/TD1303
000056818 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000056818 590__ $$a3.08$$b2016
000056818 591__ $$aPARASITOLOGY$$b9 / 36 = 0.25$$c2016$$dQ1$$eT1
000056818 592__ $$a1.534$$b2016
000056818 593__ $$aParasitology$$c2016$$dQ1
000056818 593__ $$aInfectious Diseases$$c2016$$dQ1
000056818 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000056818 700__ $$aSprong, H.
000056818 700__ $$aCabezas-Cruz, A.
000056818 700__ $$aFuente, De La
000056818 700__ $$0(orcid)0000-0002-0308-1390$$aRamo, A.$$uUniversidad de Zaragoza
000056818 700__ $$aCoipan, E.C.
000056818 7102_ $$11009$$2773$$aUniversidad de Zaragoza$$bDpto. Patología Animal$$cÁrea Sanidad Animal
000056818 773__ $$g9, 1 (2016), 517 [15 pp.]$$pParasites & Vectors$$tParasites and Vectors$$x1756-3305
000056818 8564_ $$s2521268$$uhttps://zaguan.unizar.es/record/56818/files/texto_completo.pdf$$yVersión publicada
000056818 8564_ $$s85870$$uhttps://zaguan.unizar.es/record/56818/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000056818 909CO $$ooai:zaguan.unizar.es:56818$$particulos$$pdriver
000056818 951__ $$a2020-02-21-13:29:52
000056818 980__ $$aARTICLE