57733 20210121114509.0 doi 10.1039/c4nj02071e sideral 89623 ART-2015-89623 eng Fedeli, E. Self-assembling amphiphilic Janus dendrimers: Mesomorphic properties and aggregation in water 2015 Access copy available to the general public Unrestricted The self-assembly behaviour both in bulk and in water of amphiphilic dendrimeric derivatives based on bis-MPA is the central theme of this article. The designed molecules possess two parts with different polarity// this feature is the key factor that forces their self-assembly in water into supramolecular architectures, due to hydrophobic interactions between the lipophilic fractions of the molecules, and the appearance of mesomorphic order in bulk in response to a variation of temperature (thermotropic liquid crystals). The effects provoked by the hydrophilic/lipophilic balance of the molecule were studied varying the generation of the corresponding dendrons and combining them via CuAAC click chemistry in order to obtain symmetrical and unsymmetrical final Janus dendrimers. The ability of the aggregates formed in water to encapsulate hydrophobic drugs has also been explored. info:eu-repo/grantAgreement/ES/MINECO/MAT2012-38538-C03-01 info:eu-repo/grantAgreement/ES/MINECO/CTQ2012-35692 info:eu-repo/grantAgreement/EC/FP7/215884/EU/Functional liquid Crystalline dendrimers: Synthesis of New Materials, Resource for New Applications/DENDREAMERS info:eu-repo/grantAgreement/ES/DGA/E04 info:eu-repo/semantics/openAccess by-nc http://creativecommons.org/licenses/by-nc/3.0/es/ 3.277 2015 CHEMISTRY, MULTIDISCIPLINARY 49 / 163 = 0.301 2015 Q2 T1 0.935 2015 Chemistry (miscellaneous) 2015 Q1 Materials Chemistry 2015 Q1 Catalysis 2015 Q2 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion (orcid)0000-0001-6584-6603 Lancelot, A. Universidad de Zaragoza (orcid)0000-0001-9866-6633 Serrano, J.L. Universidad de Zaragoza Calvo, P. (orcid)0000-0001-7091-077X Sierra, T. Universidad de Zaragoza 2013 765 Universidad de Zaragoza Dpto. Química Orgánica Área Química Orgánica 39, 3 (2015), 1960-1967 New j. chem. NEW JOURNAL OF CHEMISTRY 1144-0546 764516 http://zaguan.unizar.es/record/57733/files/texto_completo.pdf Postprint 118168 http://zaguan.unizar.es/record/57733/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:57733 articulos driver 2021-01-21-10:55:42 ARTICLE