Bioeutectic® ceramics for biomedical application obtained by laser floating zone method. In vivo evaluation

De Aza, P.N. ; Peña, J.I. (Universidad de Zaragoza) ; Luklinska, Z.B. ; Meseguer-Olmo, L.

Resumen: In this study, the Bioeutectic® blocks were inserted into the critical size defects of eight rabbits, using both tibiae, and the physical and chemical nature of the remodeled interface between the Bioeutectic® implants and the surrounding bone were performed at four and 15 months. The results showed a new fully mineralized bone growing in direct contact with the implants. The ionic exchange, taking place at the implant interface with the body fluids was essential in the process of the implant integration through a dissolution-precipitation-transformation mechanism. The study found the interface biologically and chemically active over the 15 months implantation period. The osteoblastic cells migrated towards the interface and colonized the surface at the contact areas with the bone. The new developed apatite structure of porous morphology mimics natural bone.

Idioma: Inglés

DOI: 10.3390/ma7042395

Año: 2014

Publicado en: MATERIALS 7, 4 (2014), 2395-2410
ISSN: 1996-1944

Factor impacto JCR: 2.651 (2014)

Categ. JCR: MATERIALS SCIENCE, MULTIDISCIPLINARY rank: 55 / 260 = 0.212 (2014) - Q1 - T1

Financiación: info:eu-repo/grantAgreement/EC/FP7/314630/EU/DEVELOPMENT OF NEW UV LASER FOR CUSTOMIZATION AT INDUSTRIAL LEVEL THROUGH HIGH QUALITY MARKING ON DIFFERNT MATERIALS/UV-Marking

Tipo y forma: Artículo (Versión definitiva)

Área (Departamento): Área Cienc.Mater. Ingen.Metal. (Dpto. Ciencia Tecnol.Mater.Fl.)