57838 20170503134900.0 doi 10.1038/bjc.2014.38 sideral 86486 ART-2014-86486 eng Bujanda, L. Effect of oral anticoagulants on the outcome of faecal immunochemical test 2014 Access copy available to the general public Unrestricted Background: We aimed to evaluate whether oral anticoagulants (OACs) alter faecal immunochemical test (FIT) performance in average-risk colorectal cancer (CRC) screening. Methods: Individuals aged 50–69 years were invited to receive one FIT sample (cutoff 75¿ng¿ml–1) between November 2008 and June 2011. Results: Faecal immunochemical test was positive in 9.3% (21 out of 224) of users of OAC and 6.2% (365 out of 5821) of non-users (P-trend=0.07). The positive predictive value (PPV) for advanced neoplasia (AN) in non-users was 50.4% vs 47.6% in users (odds ratio, 0.70; 95% CI, 0.3–1.8; P=0.5). The PPV for AN in OAC more antiplatelets (aspirin or clopidogrel) was 75% (odds ratio, 2; 95% CI, 0.4–10.8; P=0.4). Conclusions: Oral anticoagulant did not significantly modify the PPV for AN in this population-based colorectal screening program. The detection rate of advanced adenoma was higher in the combination OAC more antiplatelets. info:eu-repo/grantAgreement/ES/ISCIII/PI08-90717 info:eu-repo/semantics/openAccess by-nc-sa http://creativecommons.org/licenses/by-nc-sa/3.0/es/ 4.836 2014 ONCOLOGY 34 / 209 = 0.163 2014 Q1 T1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Sarasqueta, C. (orcid)0000-0001-5932-2889 Lanas, Á. Universidad de Zaragoza Quintero, E. Cubiella, J. Hernandez, V. Morillas, J.D. Perez-Fernández, T. Salas, D. Andreu, M. Carballo, F. Bessa, X. Portillo, I. Jover, R. Balaguer, F. Cosme, A. Castells, A. 1007 610 Universidad de Zaragoza Departamento de Medicina, Psiquiatría y Dermatología Medicina 110, 5 (2014), 1334-1337 Br. J. Cancer BRITISH JOURNAL OF CANCER 0007-0920 122640 http://zaguan.unizar.es/record/57838/files/texto_completo.pdf Versión publicada 102282 http://zaguan.unizar.es/record/57838/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:57838 articulos driver 2017-05-03-13:43:44 ARTICLE