000057856 001__ 57856
000057856 005__ 20200221144255.0
000057856 0247_ $$2doi$$a10.1371/journal.pntd.0004962
000057856 0248_ $$2sideral$$a96713
000057856 037__ $$aART-2016-96713
000057856 041__ $$aeng
000057856 100__ $$0(orcid)0000-0001-6140-2423$$aMachicado, C.
000057856 245__ $$aAssociation of Fasciola hepatica Infection with Liver Fibrosis, Cirrhosis, and Cancer: A Systematic Review
000057856 260__ $$c2016
000057856 5060_ $$aAccess copy available to the general public$$fUnrestricted
000057856 5203_ $$aBackground: Fascioliasis has been sporadically associated with chronic liver disease on previous studies. In order to describe the current evidence, we carried out a systematic review to assess the association between fascioliasis with liver fibrosis, cirrhosis and cancer. Methodology and Principal Findings: A systematic search of electronic databases (PubMed, LILACS, Scopus, Embase, Cochrane, and Scielo) was conducted from June to July 2015 and yielded 1, 557 published studies. Among 21 studies that met inclusion and exclusion criteria, 12 studies explored the association of F. hepatica with liver fibrosis, 4 with liver cirrhosis, and 5 with cancer. Globally these studies suggested the ability of F. hepatica to promote liver fibrosis and cirrhosis. The role of F. hepatica in cancer is unknown. Given the heterogeneity of the studies, a meta-analysis could not be performed. Conclusions: Future high-quality studies are needed to determine the role of F. hepatica on the development of liver fibrosis, liver cirrhosis, and cancer in humans.
000057856 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000057856 590__ $$a3.834$$b2016
000057856 591__ $$aTROPICAL MEDICINE$$b1 / 19 = 0.053$$c2016$$dQ1$$eT1
000057856 591__ $$aPARASITOLOGY$$b6 / 36 = 0.167$$c2016$$dQ1$$eT1
000057856 592__ $$a2.456$$b2016
000057856 593__ $$aInfectious Diseases$$c2016$$dQ1
000057856 593__ $$aPublic Health, Environmental and Occupational Health$$c2016$$dQ1
000057856 593__ $$aPharmacology, Toxicology and Pharmaceutics (miscellaneous)$$c2016$$dQ1
000057856 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000057856 700__ $$aMachicado, J.D.
000057856 700__ $$aMaco, V.
000057856 700__ $$aTerashima, A.
000057856 700__ $$aMarcos, L.A.
000057856 773__ $$g10, 9 (2016), 0004962 [11 pp]$$pPLoS negl. trop. dis.$$tPLoS Neglected Tropical Diseases$$x1935-2727
000057856 8564_ $$s1450640$$uhttps://zaguan.unizar.es/record/57856/files/texto_completo.pdf$$yVersión publicada
000057856 8564_ $$s83314$$uhttps://zaguan.unizar.es/record/57856/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000057856 909CO $$ooai:zaguan.unizar.es:57856$$particulos$$pdriver
000057856 951__ $$a2020-02-21-13:29:40
000057856 980__ $$aARTICLE