000057864 001__ 57864
000057864 005__ 20170504092420.0
000057864 0247_ $$2doi$$a10.1371/journal.pone.0086914
000057864 0248_ $$2sideral$$a86430
000057864 037__ $$aART-2014-86430
000057864 041__ $$aeng
000057864 100__ $$aBammann, K.
000057864 245__ $$aEarly life course risk factors for childhood obesity: The IDEFICS case-control study
000057864 260__ $$c2014
000057864 5060_ $$aAccess copy available to the general public$$fUnrestricted
000057864 5203_ $$aBackground:
The early life course is assumed to be a critical phase for childhood obesity; however the significance of single factors and their interplay is not well studied in childhood populations.
Objectives:
The investigation of pre-, peri- and postpartum risk factors on the risk of obesity at age 2 to 9.
Methods:
A case-control study with 1,024 1:1-matched case-control pairs was nested in the baseline survey (09/2007–05/2008) of the IDEFICS study, a population-based intervention study on childhood obesity carried out in 8 European countries in pre- and primary school settings. Conditional logistic regression was used for identification of risk factors.
Results:
For many of the investigated risk factors, we found a raw effect in our study. In multivariate models, we could establish an effect for gestational weight gain (adjusted OR?=?1.02; 95%CI 1.00–1.04), smoking during pregnancy (adjusted OR?=?1.48; 95%CI 1.08–2.01), Caesarian section (adjusted OR?=?1.38; 95%CI 1.10–1.74), and breastfeeding 4 to 11 months (adjusted OR?=?0.77; 95%CI 0.62–0.96). Birth weight was related to lean mass rather than to fat mass, the effect of smoking was found only in boys, but not in girls. After additional adjustment for parental BMI and parental educational status, only gestational weight gain remained statistically significant. Both, maternal as well as paternal BMI were the strongest risk factors in our study, and they confounded several of the investigated associations.
Conclusions:
Key risk factors of childhood obesity in our study are parental BMI and gestational weight gain; consequently prevention approaches should target not only children but also adults. The monitoring of gestational weight seems to be of particular importance for early prevention of childhood obesity.
000057864 536__ $$9info:eu-repo/grantAgreement/EUR/FP6/FOOD-016181
000057864 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000057864 590__ $$a3.234$$b2014
000057864 591__ $$aMULTIDISCIPLINARY SCIENCES$$b9 / 57 = 0.158$$c2014$$dQ1$$eT1
000057864 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000057864 700__ $$aPeplies, J.
000057864 700__ $$aDe Henauw, S.
000057864 700__ $$aHunsberger, M.
000057864 700__ $$aMolnar, D.
000057864 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, L.A.$$uUniversidad de Zaragoza
000057864 700__ $$aTornaritis, M.
000057864 700__ $$aVeidebaum, T.
000057864 700__ $$aAhrens, W.
000057864 700__ $$aSiani, A.
000057864 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDepartamento de Fisiatría y Enfermería$$cEnfermería
000057864 773__ $$g9, 2 (2014), e-86914 [7 pp]$$pPLoS One$$tPLoS One$$x1932-6203
000057864 8564_ $$s171057$$uhttps://zaguan.unizar.es/record/57864/files/texto_completo.pdf$$yVersión publicada
000057864 8564_ $$s117692$$uhttps://zaguan.unizar.es/record/57864/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000057864 909CO $$ooai:zaguan.unizar.es:57864$$particulos$$pdriver
000057864 951__ $$a2017-05-04-09:18:56
000057864 980__ $$aARTICLE