57914 20171107095244.0 doi 10.1155/2013/341269 sideral 84616 ART-2013-84616 eng (orcid)0000-0003-0349-9997 Pinilla, I. Universidad de Zaragoza Changes in frequency-doubling perimetry in patients with type i diabetes prior to retinopathy 2013 Access copy available to the general public Unrestricted Purpose. To evaluate the ability of frequency-doubling technology (FDT) perimetry in detecting visual field defects in young adults with type I diabetes prior to retinopathy or with minor retinovascular changes. Methods. This comparative cross-sectional study included 30 healthy subjects and 73 age-matched patients with type I diabetes mellitus. All subjects underwent a full ocular examination including an FDT with the threshold C-20-5 strategy. Only one eye per subject was randomly included in the statistical analysis. FDT results and time to perform the test were compared between the groups. Results. The mean age was 27.1 years in the control group and 26.6 years in the diabetic group ( ). The mean period from the onset of diabetes was years, while minimal retinovascular changes were observed in 18 eyes. Mean deviation of FDT did not differ between the groups. Although global indices of FDT were within normal limits, pattern standard deviation of FDT was higher in the diabetic group ( ). The area under the receiver operating characteristic curve was 0.647 for pattern standard deviation of FDT (standard error = 0.052; ). Conclusion. FDT can detect retinal dysfunctions in diabetic patients prior to the onset of significant vascular complications. info:eu-repo/grantAgreement/ES/ISCIII/PI08-0976 info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI11-01239 info:eu-repo/grantAgreement/ES/DGA/B99 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 0.0 2013 MEDICINE, RESEARCH & EXPERIMENTAL BIOTECHNOLOGY & APPLIED MICROBIOLOGY info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion (orcid)0000-0002-2914-2593 Ferreras, A. Universidad de Zaragoza Idoipe, M. (orcid)0000-0002-5621-1937 Sanchez-Cano, A. Universidad de Zaragoza Perez-Garcia, D. Herrera, L.X. Pinilla, M.J. Abecia, E. 1004 646 Universidad de Zaragoza Departamento de Cirugía, Ginecología y Obstetricia Oftalmología 2002 647 Universidad de Zaragoza Departamento de Física Aplicada Optica 2013 (2013), 341269 [7 pp] BioMed res. int. BioMed Research International 2314-6133 1887175 http://zaguan.unizar.es/record/57914/files/texto_completo.pdf Versión publicada 99389 http://zaguan.unizar.es/record/57914/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:57914 articulos driver 2017-11-07-09:50:05 ARTICLE