58352 20200221144225.0 doi 10.2174/1570179412666150914200035 sideral 97064 ART-2016-97064 eng (orcid)0000-0001-7773-9418 Matute, R. Universidad de Zaragoza Recent advances in the preparation of enantiomerically pure hydroxylamines from nitrones 2016 Access copy available to the general public Unrestricted This review covers the recent advances in the synthesis of enantiomerically pure hydroxylamine’s employing nitrones as starting materials. Nucleophilic additions of organometallic reagents to nitrones are the most common way for introducing a hydroxyamino group into carbon skeletons with the concomitant formation of a new carbon-carbon bond. Addition of nucleophiles derived from enolates, cyanide or fluorinated derivatives allows the preparation of complex structures. Radical additions and, in particular samarium diiodidemediated reductive coupling of nitrones with carbonyl compounds and a, ß-unsaturated esters have also been considered. All these approaches provide efficient methods of preparation of enantiomerically pure hydroxylamine’s that are valuable synthetic intermediates. info:eu-repo/grantAgreement/ES/DGA/E10 info:eu-repo/grantAgreement/ES/MICINN/CTQ2013-44367-C2-1-P info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 1.917 2016 CHEMISTRY, ORGANIC 35 / 59 = 0.593 2016 Q3 T2 0.565 2016 Organic Chemistry 2016 Q3 Biochemistry 2016 Q3 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion García-Viñuales, S. Hayes, H. (orcid)0000-0002-2855-4801 Ghirardello, M. Universidad de Zaragoza Darù, A. (orcid)0000-0003-3433-6701 Tejero, T. Universidad de Zaragoza (orcid)0000-0001-8355-2289 Delso, I. Universidad de Zaragoza (orcid)0000-0002-2202-3460 Merino, P. Universidad de Zaragoza 2013 765 Universidad de Zaragoza Dpto. Química Orgánica Área Química Orgánica 5005 790 Universidad de Zaragoza Dpto. Ing.Quím.Tecnol.Med.Amb. Área Tecnologi. Medio Ambiente 13, 5 (2016), 669-686 Curr. Org. Synth. CURRENT ORGANIC SYNTHESIS 1570-1794 654293 http://zaguan.unizar.es/record/58352/files/texto_completo.pdf Postprint 48822 http://zaguan.unizar.es/record/58352/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:58352 articulos driver 2020-02-21-13:17:10 ARTICLE