60674 20190709135439.0 doi 10.1039/c7ra00687j sideral 98092 ART-2017-98092 eng Bonvin, D. Controlling structural and magnetic properties of IONPs by aqueous synthesis for improved hyperthermia 2017 Access copy available to the general public Unrestricted Iron oxide nanoparticles (IONPs) were synthesized by a novel aqueous synthesis route which combines co-precipitation (CP) and hydrothermal (HT) treatment, termed CP + HT, and compared with IONPs obtained by the standard CP method. Properties of both types of IONPs, including their morphology, diameters, composition, structure and crystallinity, as well as magnetic properties and toxicity were studied and correlated with the synthesis route. Their potential application as mediators for hyperthermia treatment has been evaluated by the specific absorption rate (SAR). Studies showed that IONPs obtained by a novel CP + HT route have a more controlled morphology, structure and crystallinity, leading to better magnetic properties and SAR as compared to IONPs synthesized by CP. Reported IONPs are also not toxic as shown by two assays in two cell lines. These results suggest that our IONPs are suitable for biomedical applications, especially as mediators for the hyperthermia treatment. info:eu-repo/grantAgreement/ES/MINECO/MAT2014-54975-R info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 2.936 2017 CHEMISTRY, MULTIDISCIPLINARY 71 / 171 = 0.415 2017 Q2 T2 0.863 2017 Chemistry (miscellaneous) 2017 Q1 Chemical Engineering (miscellaneous) 2017 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Arakcheeva, A. (orcid)0000-0003-0828-3212 Millán, A. Universidad de Zaragoza (orcid)0000-0001-7625-4806 Piñol, R. Universidad de Zaragoza Hofmann, H. Mionic Ebersold, M. 2003 395 Universidad de Zaragoza Dpto. Física Materia Condensa. Área Física Materia Condensada 7, 22 (2017), 13159-13170 RSC ADVANCES RSC Advances 2046-2069 1157087 http://zaguan.unizar.es/record/60674/files/texto_completo.pdf Versión publicada 119644 http://zaguan.unizar.es/record/60674/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:60674 articulos driver 2019-07-09-11:35:36 ARTICLE