60681 20190709135454.0 doi 10.1186/s12906-017-1638-y sideral 98230 ART-2017-98230 eng Sanada, K. Effects of mindfulness-based interventions on biomarkers in healthy and cancer populations: A systematic review 2017 Access copy available to the general public Unrestricted Background: Only a small number of articles have investigated the relationship between mindfulness-based interventions (MBIs) and biomarkers. The aim of this systematic review was to study the effect of MBIs on specific biomarkers (cytokines, neuropeptides and C-reactive protein (CRP)) in both healthy subjects and cancer patients. Methods: A search was conducted using PubMed, EMBASE, PsycINFO and the Cochrane library between 1980 and September 2016. Results: A total of 13 studies with 1110 participants were included. In the healthy population, MBIs had no effect on cytokines, but were found to increase the levels of the neuropeptide insulin-like growth factor 1 (IGF-1). With respect to neuropeptide Y, despite the absence of post-intervention differences, MBIs may enhance recovery from stress. With regard to CRP, MBIs could be effective in lower Body Mass Index (BMI) individuals. In cancer patients, MBIs seem to have some effect on cytokine levels, although it was not possible to determine which specific cytokines were affected. One possibility is that MBIs might aid recovery of the immune system, increasing the production of interleukin (IL)-4 and decreasing interferon gamma (IFN-¿). Conclusions: MBIs may be involved in changes from a depressive/carcinogenic profile to a more normalized one. However, given the complexity and different contexts of the immune system, and the fact that this investigation is still in its preliminary stage, additional randomized controlled trials are needed to further establish the impact of MBI programmes on biomarkers in both clinical and non-clinical populations. info:eu-repo/grantAgreement/ES/FIS/PI13-01637 info:eu-repo/grantAgreement/ES/ISCIII/RD12-0005 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 2.109 2017 INTEGRATIVE & COMPLEMENTARY MEDICINE 8 / 27 = 0.296 2017 Q2 T1 0.858 2017 Complementary and Alternative Medicine 2017 Q1 Medicine (miscellaneous) 2017 Q2 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion (orcid)0000-0002-7931-4082 Alda Díez, M. Universidad de Zaragoza (orcid)0000-0001-6261-3724 Salas Valero, M. Pérez-Yus, M.C. Demarzo, M.M.P. (orcid)0000-0001-5677-1662 Montero-Marín, J. García-Toro, M. (orcid)0000-0002-3797-4218 García-Campayo, J. Universidad de Zaragoza 1007 745 Universidad de Zaragoza Dpto. Medicina, Psiqu. y Derm. Area Psiquiatría 17, 1 (2017), 125 BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE 1472-6882 601887 http://zaguan.unizar.es/record/60681/files/texto_completo.pdf Versión publicada 102317 http://zaguan.unizar.es/record/60681/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:60681 articulos driver 2019-07-09-11:42:38 ARTICLE