000061323 001__ 61323
000061323 005__ 20210121114524.0
000061323 0248_ $$2sideral$$a89411
000061323 037__ $$aART-2015-89411
000061323 041__ $$aeng
000061323 100__ $$aFiuza-Luces, C.
000061323 245__ $$aUnderstanding graft-versus-host disease. Preliminary findings regarding the effects of exercise in affected patients
000061323 260__ $$c2015
000061323 5060_ $$aAccess copy available to the general public$$fUnrestricted
000061323 5203_ $$aAdvances in this century regarding allogeneic hematopoietic stem cell transplantation (allo-HSCT) have led to an expanding population of long-term survivors, many of whom suffer severe side effects, particularly those related to graft-versushost disease (GVHD), a potentially multi-systemic disorder caused by immunoeffector donor lymphocytes that destroy host tissues. The GVHD, especially in its chronic form (cGVHD), generates considerable morbidity and compromises the physical capacity of patients. We have reviewed the main pathophysiological aspects of the disease as well as the data available on the effects of exercise in GVHD, based on animal and human patient research. Although exercise training as an adjunct therapy to improve health outcomes after allo-HSCT shows promise (particularly, this lifestyle intervention can improve physical fitness and possibly immune function while attenuating fatigue), there is a need for more randomized control trials that focus specifically on GVHD.
000061323 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000061323 590__ $$a4.294$$b2015
000061323 591__ $$aSPORT SCIENCES$$b5 / 82 = 0.061$$c2015$$dQ1$$eT1
000061323 591__ $$aIMMUNOLOGY$$b39 / 151 = 0.258$$c2015$$dQ2$$eT1
000061323 592__ $$a1.799$$b2015
000061323 593__ $$aSports Science$$c2015$$dQ1
000061323 593__ $$aImmunology$$c2015$$dQ1
000061323 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000061323 700__ $$0(orcid)0000-0001-8374-9081$$aGaratachea, N.$$uUniversidad de Zaragoza
000061323 700__ $$aSimpson, RJ.
000061323 700__ $$aBerger, NA.
000061323 700__ $$aRamírez, M.
000061323 700__ $$aLucia, A.
000061323 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor.
000061323 773__ $$g21 (2015), 80-112$$pExerc. immunol. rev.$$tEXERCISE IMMUNOLOGY REVIEW$$x1077-5552
000061323 8564_ $$s3201176$$uhttps://zaguan.unizar.es/record/61323/files/texto_completo.pdf$$yVersión publicada
000061323 8564_ $$s9948$$uhttps://zaguan.unizar.es/record/61323/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000061323 909CO $$ooai:zaguan.unizar.es:61323$$particulos$$pdriver
000061323 951__ $$a2021-01-21-11:05:03
000061323 980__ $$aARTICLE