61435 20200910145136.0 doi 10.1088/0967-3334/37/7/1004 sideral 94143 ART-2016-94143 eng Romero, Daniel Ischemia detection from morphological QRS angles changes 2016 Access copy available to the general public Unrestricted In this paper, an ischemia detector is presented based on the analysis of QRS-derived angles. The detector has been developed by modeling ischemic effects on the QRS angles as a gradual change with a certain transition time and assuming a Laplacian additive modeling error contaminating the angle series. Both standard and non-standard leads were used for analysis. Non- standard leads were obtained by applying the PCA technique over specific lead subsets to represent different potential locations of the ischemic zone. The performance of the proposed detector was tested over a population of 79 patients undergoing percutaneous coronary intervention in one of the major coronary arteries (LAD (n = 25), RCA (n = 16) and LCX (n = 38)). The best detection performance, obtained for standard ECG leads, was achieved in the LAD group with values of sensitivity and specificity of Se = 90.9%, Sp = 95.4%, followed by the RCA group with Se = 88.9%, Sp = 94.4 and the LCX group with Se = 86.1%, Sp = 94.4%, notably outperforming detection based on the ST series in all cases, with the same detector structure. The timing of the detected ischemic events ranged from 30 s up to 150 s (mean = 66.8 s) following the start of occlusion. We conclude that changes in the QRS angles can be used to detect acute myocardial ischemia info:eu-repo/grantAgreement/ES/MINECO/TEC2013-42140-R info:eu-repo/grantAgreement/ES/MINECO/TIN2013-41998-R info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 2.058 2016 ENGINEERING, BIOMEDICAL 37 / 77 = 0.481 2016 Q2 T2 PHYSIOLOGY 50 / 84 = 0.595 2016 Q3 T2 BIOPHYSICS 49 / 73 = 0.671 2016 Q3 T3 0.688 2016 Biomedical Engineering 2016 Q2 Biophysics 2016 Q2 Physiology 2016 Q3 Physiology (medical) 2016 Q3 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion (orcid)0000-0002-7503-3339 Martínez, Juan Pablo Universidad de Zaragoza (orcid)0000-0003-3434-9254 Laguna, Pablo Universidad de Zaragoza (orcid)0000-0002-1960-407X Pueyo, Esther Universidad de Zaragoza 5008 800 Universidad de Zaragoza Dpto. Ingeniería Electrón.Com. Área Teoría Señal y Comunicac. 37, 7 (2016), 1004-1023 Physiol. meas. PHYSIOLOGICAL MEASUREMENT 0967-3334 274656 http://zaguan.unizar.es/record/61435/files/texto_completo.pdf Postprint 79987 http://zaguan.unizar.es/record/61435/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:61435 articulos driver 2020-09-10-14:38:37 ARTICLE