61571 20181123104108.0 sideral 98585 ART-2016-98585 eng (orcid)0000-0003-4130-5866 Ramirez, J. Universidad de Zaragoza An index for T-wave pointwise amplitude variability quantification 2016 Access copy available to the general public Unrestricted The comparison between the pointwise amplitude of different T-waves provides insight into ventricular repolarization liability. However, T-wave pointwise amplitude variability can be confounded by time-domain variability. We, first, compared two algorithms for removing (warping) time-domain variability, one using the original and another one using a transformed T-wave (SRSF). We, next, compared the robustness against noise of two markers, dy and da, of pointwise amplitude variability, after warping the underlying temporal variability with the preferred warping algorithm. dy was obtained from the transformed T-waves while da was proposed in this work and was derived from the original T-waves. We, finally, used the most robust marker to measure the T-wave pointwise amplitude variability between every T-wave recorded during a Tilt test and their mean T-wave. Results showed that the preferred warping algorithm was the SRSF because it is not affected by differences between the amplitudes of the original T-waves. In addition, the marker da presented lower relative error values than dy for every level of noise. The analysis of electrocardiogram records showed that da was significantly lower during the tilt than in supine position (5.5 % vs 6.5 %, p<0.01). In conclusion, da robustly quantifies physiological variabilities of the T-wave amplitude, showing its potential to be used as an arrhythmic risk predictor in future clinical situations. info:eu-repo/grantAgreement/ES/DGA/T96 info:eu-repo/grantAgreement/ES/MINECO/TIN2013-41998-R info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Orini, M. Derek Tucker, J. (orcid)0000-0002-1960-407X Pueyo, E. Universidad de Zaragoza (orcid)0000-0003-3434-9254 Laguna, P. Universidad de Zaragoza 5008 800 Universidad de Zaragoza Dpto. Ingeniería Electrón.Com. Área Teoría Señal y Comunicac. 43 (2016), 49-52 Comput. cardiol. Computing in Cardiology 2325-8861 http://ieeexplore.ieee.org/document/7868676/ Texto completo de la revista 265374 http://zaguan.unizar.es/record/61571/files/texto_completo.pdf Versión publicada 115553 http://zaguan.unizar.es/record/61571/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:61571 articulos driver 2018-11-23-10:33:23 ARTICLE