000061945 001__ 61945
000061945 005__ 20190709135502.0
000061945 0247_ $$2doi$$a10.1038/s41598-017-04364-7
000061945 0248_ $$2sideral$$a100709
000061945 037__ $$aART-2017-100709
000061945 041__ $$aeng
000061945 100__ $$0(orcid)0000-0001-6859-099X$$aFiasconaro, A.$$uUniversidad de Zaragoza
000061945 245__ $$aActive translocation of a semiflexible polymer assisted by an ATP-based molecular motor
000061945 260__ $$c2017
000061945 5060_ $$aAccess copy available to the general public$$fUnrestricted
000061945 5203_ $$aIn this work we study the assisted translocation of a polymer across a membrane nanopore, inside which a molecular motor exerts a force fuelled by the hydrolysis of ATP molecules. In our model the motor switches to its active state for a fixed amount of time, while it waits for an ATP molecule which triggers the motor, during an exponentially distributed time lapse. The polymer is modelled as a beads-springs chain with both excluded volume and bending contributions, and moves in a stochastic three dimensional environment modelled with a Langevin dynamics at a fixed temperature. The resulting dynamics shows a Michaelis-Menten translocation velocity that depends on the chain flexibility. The scaling behavior of the mean translocation time with the polymer length for different bending values is also investigated.
000061945 536__ $$9info:eu-repo/grantAgreement/ES/MINECO/FIS2014-55867-P
000061945 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000061945 590__ $$a4.122$$b2017
000061945 591__ $$aMULTIDISCIPLINARY SCIENCES$$b12 / 64 = 0.188$$c2017$$dQ1$$eT1
000061945 592__ $$a1.533$$b2017
000061945 593__ $$aMultidisciplinary$$c2017$$dQ1
000061945 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000061945 700__ $$0(orcid)0000-0003-0698-6555$$aMazo, J.J.$$uUniversidad de Zaragoza
000061945 700__ $$0(orcid)0000-0002-9551-624X$$aFalo, F.$$uUniversidad de Zaragoza
000061945 7102_ $$12003$$2395$$aUniversidad de Zaragoza$$bDpto. Física Materia Condensa.$$cÁrea Física Materia Condensada
000061945 773__ $$g7 (2017), [11 pp]$$pSci. rep.$$tScientific reports$$x2045-2322
000061945 8564_ $$s1857592$$uhttps://zaguan.unizar.es/record/61945/files/texto_completo.pdf$$yVersión publicada
000061945 8564_ $$s112112$$uhttps://zaguan.unizar.es/record/61945/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000061945 909CO $$ooai:zaguan.unizar.es:61945$$particulos$$pdriver
000061945 951__ $$a2019-07-09-11:47:00
000061945 980__ $$aARTICLE