61945 20190709135502.0 doi 10.1038/s41598-017-04364-7 sideral 100709 ART-2017-100709 eng (orcid)0000-0001-6859-099X Fiasconaro, A. Universidad de Zaragoza Active translocation of a semiflexible polymer assisted by an ATP-based molecular motor 2017 Access copy available to the general public Unrestricted In this work we study the assisted translocation of a polymer across a membrane nanopore, inside which a molecular motor exerts a force fuelled by the hydrolysis of ATP molecules. In our model the motor switches to its active state for a fixed amount of time, while it waits for an ATP molecule which triggers the motor, during an exponentially distributed time lapse. The polymer is modelled as a beads-springs chain with both excluded volume and bending contributions, and moves in a stochastic three dimensional environment modelled with a Langevin dynamics at a fixed temperature. The resulting dynamics shows a Michaelis-Menten translocation velocity that depends on the chain flexibility. The scaling behavior of the mean translocation time with the polymer length for different bending values is also investigated. info:eu-repo/grantAgreement/ES/MINECO/FIS2014-55867-P info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 4.122 2017 MULTIDISCIPLINARY SCIENCES 12 / 64 = 0.188 2017 Q1 T1 1.533 2017 Multidisciplinary 2017 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion (orcid)0000-0003-0698-6555 Mazo, J.J. Universidad de Zaragoza (orcid)0000-0002-9551-624X Falo, F. Universidad de Zaragoza 2003 395 Universidad de Zaragoza Dpto. Física Materia Condensa. Área Física Materia Condensada 7 (2017), [11 pp] Sci. rep. Scientific reports 2045-2322 1857592 http://zaguan.unizar.es/record/61945/files/texto_completo.pdf Versión publicada 112112 http://zaguan.unizar.es/record/61945/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:61945 articulos driver 2019-07-09-11:47:00 ARTICLE