61989 20190709135434.0 doi 10.1371/journal.pone.0180549 sideral 100957 ART-2017-100957 eng Alcalde Cuesta, Fernando Suppressors of selection 2017 Access copy available to the general public Unrestricted Inspired by recent works on evolutionary graph theory, an area of growing interest in mathematical and computational biology, we present examples of undirected structures acting as suppressors of selection for any fitness value r > 1. This means that the average fixation probability of an advantageous mutant or invader individual placed at some node is strictly less than that of this individual placed in a well-mixed population. This leads the way to study more robust structures less prone to invasion, contrary to what happens with the amplifiers of selection where the fixation probability is increased on average for advantageous invader individuals. A few families of amplifiers are known, although some effort was required to prove it. Here, we use computer aided techniques to find an exact analytical expression of the fixation probability for some graphs of small order (equal to 6, 8 and 10) proving that selection is effectively reduced for r > 1. Some numerical experiments using Monte Carlo methods are also performed for larger graphs and some variants. info:eu-repo/grantAgreement/ES/DGA/E15 info:eu-repo/grantAgreement/ES/MICINN/MTM2013-46337-C2-2-P info:eu-repo/grantAgreement/ES/MICINN/MTM2016-77642-C2-2-P info:eu-repo/grantAgreement/ES/UZ/CUD2015-10 info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 2.766 2017 MULTIDISCIPLINARY SCIENCES 15 / 64 = 0.234 2017 Q1 T1 1.164 2017 Agricultural and Biological Sciences (miscellaneous) 2017 Q1 Medicine (miscellaneous) 2017 Q1 Biochemistry, Genetics and Molecular Biology (miscellaneous) 2017 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion González Sequeiros, Pablo (orcid)0000-0002-1184-5901 Lozano Rojo, Álvaro 12, 7 (2017), [7 pp.] PLoS One PloS one 1932-6203 428001 http://zaguan.unizar.es/record/61989/files/texto_completo.pdf Versión publicada 15856 http://zaguan.unizar.es/record/61989/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:61989 articulos driver 2019-07-09-11:33:09 ARTICLE