62039 20171211140547.0 doi 10.5424/sjar/2014123-5489 sideral 87823 ART-2014-87823 eng Salazar, E. Lack of relationship between Visna/maedi infection and scrapie resistance genetic markers 2014 Access copy available to the general public Unrestricted The relationship between Visna/maedi virus (VMV) antibody status and scrapie genetic resistance of 10,611 Rasa Aragonesa sheep from 17 flocks in Aragón (Spain) was investigated. The fifteen most common PRNP gene haplotypes and genotypes were identified and the genotypes were classified into the corresponding scrapie risk groups (groups 1 to 5). ARQ (93.3%) and ARR (31.8%) were the most common haplotypes and ARQ/ARQ (56%) and ARR/ARQ (25.6%) were the most common genotypes. The frequencies of scrapie risk groups 1, 2, 3, 4 and 5 were 3.3%, 27.3%, 63.5%, 1.2% and 4.8%, respectively. Overall Visna/maedi seroprevalence was 53% and flock seroprevalence ranged between 21-86%. A random effects logistic regression model indicated that sheep VMV serological status (outcome variable) was not associated with any particular scrapie risk group. Instead, VMV seropositivity progressively increased with age, was signif icantly greater in females compared to males and varied between flocks. The absence of a relationship between VMV infection and scrapie genotypes is important for VMV control and specifically for sheep participating in an ELISA-based Visna/maedi control program. info:eu-repo/grantAgreement/ES/MICINN/AGL2007-66874-C04-02 GAN info:eu-repo/grantAgreement/ES/MINECO/AGL2010-22341-C04-02 GAN info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 0.703 2014 AGRICULTURE, MULTIDISCIPLINARY 25 / 56 = 0.446 2014 Q2 T2 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Berriatua, E. Pérez, M. Marín, B. (orcid)0000-0001-5105-6133 Acín, C. Universidad de Zaragoza (orcid)0000-0001-6016-4726 Martín-Burriel, I. Universidad de Zaragoza Reina, R. de Andrés, D. Amorena, B. (orcid)0000-0002-7173-7216 Badiola, J. J. Universidad de Zaragoza (orcid)0000-0002-2053-9842 Luján, L. Universidad de Zaragoza 1009 773 Universidad de Zaragoza Departamento de Patología Animal Sanidad Animal 1001 420 Universidad de Zaragoza Departamento de Anatomía, Embriología y Genética Animal Genética 12, 3 (2014), 676-682 Span. j. agric. res. SPANISH JOURNAL OF AGRICULTURAL RESEARCH 1695-971X 267910 http://zaguan.unizar.es/record/62039/files/texto_completo.pdf Versión publicada 106569 http://zaguan.unizar.es/record/62039/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:62039 articulos driver 2017-12-11-14:02:27 ARTICLE