000062089 001__ 62089
000062089 005__ 20190709135518.0
000062089 0247_ $$2doi$$a10.20960/nh.559
000062089 0248_ $$2sideral$$a100849
000062089 037__ $$aART-2017-100849
000062089 041__ $$aeng
000062089 100__ $$0(orcid)0000-0002-2219-3646$$aIglesia, I.
000062089 245__ $$aAssociations between insulin resistance and three B-vitamins in european adolescents: The HELENA study
000062089 260__ $$c2017
000062089 5060_ $$aAccess copy available to the general public$$fUnrestricted
000062089 5203_ $$aObjective: To assess whether adolescents with high body mass index (BMI), or fat mass index (FMI), in combination with insulin resistance (assessed with the Homeostatic Model Assessment [HOMA] index), had also lower blood vitamin B6, folate and vitamin B12 concentrations. Methods and materials: Six hundred and fifteen adolescents from the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study, with data on B-vitamins (both intakes and status), and BMI, FMI, HOMA, were selected. Intakes were assessed by two non-consecutive 24-h recalls. B-vitamins biomarkers were measured by chromatography and immunoassay. Analysis of covariance was applied to elucidate the differences in B-vitamins between combinations of groups defined according to the median of the z-scores of markers of body composition and insulin sensitivity. Results: When considering energy intakes and education of the mother in the model, in females, vitamin B6 intakes were higher in the high BMI/ high HOMA group than in the high BMI-low HOMA group. Similarly, vitamin B6 intakes were higher in the high FMI/high HOMA group than in the low FMI/low HOMA group. Plasma vitamin B12 was significantly lower in males in the high FMI/high HOMA group than in the low FMI/low HOMA group, keeping also significant their trends throughout the groups, a fact that can be observed also for females (p < 0.05). Conclusion: Adolescents with combined higher adiposity and higher HOMA insulin sensitivity showed lower vitamin B12 plasma concentrations. These differences do not seem to be explained by dietary vitamin B12 intake.
000062089 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000062089 592__ $$a0.411$$b2017
000062089 593__ $$aNutrition and Dietetics$$c2017$$dQ3
000062089 593__ $$aMedicine (miscellaneous)$$c2017$$dQ3
000062089 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000062089 700__ $$aGonzález-Gross, M.
000062089 700__ $$aHuybrechts, I.
000062089 700__ $$aDe-Miguel-Etayo, P.
000062089 700__ $$aMolnar, D.
000062089 700__ $$aManios, Y.
000062089 700__ $$aWidhalm, K.
000062089 700__ $$aGottrand, F.
000062089 700__ $$aKafatos, A.
000062089 700__ $$aMarcos, A.
000062089 700__ $$aPuerta, A.O.
000062089 700__ $$aLeclerc, C.
000062089 700__ $$aDe Henauw, S.
000062089 700__ $$aStehle, P.
000062089 700__ $$aKersting, M.
000062089 700__ $$0(orcid)0000-0002-3726-1066$$aMouratidou, T.
000062089 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, L.A.$$uUniversidad de Zaragoza
000062089 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000062089 773__ $$g34, 3 (2017), 568-577$$pNutr. hosp.$$tNUTRICION HOSPITALARIA$$x0212-1611
000062089 85641 $$uhttp://revista.nutricionhospitalaria.net/index.php/nh/article/view/559/563$$zTexto completo de la revista
000062089 8564_ $$s816424$$uhttps://zaguan.unizar.es/record/62089/files/texto_completo.pdf$$yVersión publicada
000062089 8564_ $$s15117$$uhttps://zaguan.unizar.es/record/62089/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000062089 909CO $$ooai:zaguan.unizar.es:62089$$particulos$$pdriver
000062089 951__ $$a2019-07-09-11:56:12
000062089 980__ $$aARTICLE