@article{SalordTorres:62344,
author = "Salord Torres, Francesc Xavier and Acín Tresaco, Cristina
and Bolea Bailo, Rosa María",
title = "{La reacción de hipersensibilidad tipo I en la especie
canina: dermatitis atópica canina y otras enfermedades
alérgicas}",
year = "2017",
note = "Type I Hypersensitivity reaction (immediate
hypersensitivity) is an immediate reaction that occurs when
antigen combines with preformed antibody (IgE) (created by
a sensitizing exposure to the antigen) that is attached to
mast cells triggering an instant reaction: inflammatory and
vasoactive substances are released from mast cells
granules, causing vasodilatation, oedema, eosinophil
chemotaxis, pruritus and bronchoconstriction. Important . 4
TYPE I HIPERSENSITIVITY REACTION IN THE CANINE SPECIES
Canine Atopic Dermatitis and other allergic diseases
examples in veterinary Medicine of Immediate
Hypersensitivity reactions include from systemic allergic
disorders (anaphylaxis) to specific allergic disorders such
as respiratory and ocular allergies (allergic rhinitis,
bronchitis and conjunctivitis) and food and skin allergies.
Skin allergic disorders are the most relevant in dogs,
including a multifactorial syndrome suffered from 10 to 15%
of dogs named Canine Atopic Dermatitis (CAD). In the first
decade of the 20th century the Austrian scientist Clemens
von Pirquet introduced the term 'allergy' into the world of
human medicine. Later the concept was extended to the
veterinary field and in 1941 clinical manifestations of
canine atopy first were reported in a dog affected with
seasonal allergic rhinitis. It is only in 1971 that the
clinical signs of CAD initially were described. Allergic
conditions usually are multifactorial involving both
intrinsic factors, unique to the animal, and extrinsic
factors, relating to both the environment and cutaneous
microenvironment. A thorough understanding of these factors
is needed if the condition wants to be managed successfully
via current diagnostic and therapeutic tools.",
}