63174 20200221144317.0 doi 10.2527/jas.2015-0109 sideral 97115 ART-2016-97115 eng (orcid)0000-0003-0656-554X Schauf, S. Universidad de Zaragoza Effect of sterilization and of dietary fat and carbohydrate content on food intake, activity level, and blood satiety–related hormones in female dogs 2016 Access copy available to the general public Unrestricted Animal sterilization is suggested to promote food overconsumption, although it is unknown whether this effect is mediated by variations in satiety-related hormones, which are released in response to food intake. The aim of this study was to evaluate the effect of sterilization and of the main energy-delivery nutrients, fat and nonstructural carbohydrates, on food intake, blood concentration of satiety-related hormones, and activity level in dogs. In a 2-phase experiment (phase I Ph.I], 74 d, and Ph.II, 84 d), 12 female Beagle dogs were assigned to a control group (intact in both phases) and a sterilization group (spayed 20 d before Ph.II). In each phase, dogs received a high-carbohydrate (HC) diet (313 and 105 g/kg DM starch and fat, respectively) and a high-fat (HF) diet (191 and 213 g/kg DM starch and fat, respectively), both high in total dietary fiber (>200 g/kg DM) and providing 27% ME as protein, in 2 consecutive periods following a crossover arrangement. During each period, dogs’ voluntary DMI and activity level were recorded during 5 d. Then, energy allowance was restricted to 0.7 maintenance and the level of intake of a common challenge food offered 4 h after feeding the experimental diets (challenge food intake ChFI]) was used as an index of the satiety state of dogs. Blood concentration of active ghrelin, cholecystokinin (CCK), total peptide YY (PYY), and insulin were determined before and 15, 60, 120, 240, and 360 min after feeding. Voluntary DMI was greater (P 0.10). Dogs fed the HF diet showed a lower increase of CCK at 120 (P 0.10). Dogs fed the HF diet showed a lower increase of CCK at 120 (P 0.10). Dogs fed the HF diet showed a lower increase of CCK at 120 (P 0.10). Dogs fed the HF diet showed a lower increase of CCK at 120 (P 0.10). Dogs fed the HF diet showed a lower increase of CCK at 120 (P 0.10) but led to a reduced activity level compared with control dogs (P < 0.05). In summary, dog sterilization was not associated with an impaired appetite control. Feeding dogs the HF diet led to energy overconsumption and to a lower blood elevation of CCK and PYY but was not associated with a weaker satiating effect 4 h later compared with the HC diet. info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 1.863 2016 AGRICULTURE, DAIRY & ANIMAL SCIENCE 8 / 57 = 0.14 2016 Q1 T1 1.034 2016 Animal Science and Zoology 2016 Q1 Medicine (miscellaneous) 2016 Q1 Food Science 2016 Q1 Genetics 2016 Q2 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Salas-Mani, A. Torre, C. Bosch, G. Swarts, H. (orcid)0000-0002-9282-7974 Castrillo, C. Universidad de Zaragoza 2008 700 Universidad de Zaragoza Dpto. Produc.Animal Cienc.Ali. Área Producción Animal 94, 10 (2016), 4239-4250 J. anim. sci. JOURNAL OF ANIMAL SCIENCE 0021-8812 495376 http://zaguan.unizar.es/record/63174/files/texto_completo.pdf Versión publicada 114484 http://zaguan.unizar.es/record/63174/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:63174 articulos driver 2020-02-21-13:39:34 ARTICLE