63192 20190709135505.0 doi 10.1136/bmjopen-2017-016546 sideral 101946 ART-2017-101946 eng Aranaz Andrés, J.M. Comparison of two methods to estimate adverse events in the IBEAS Study (Ibero-American study of adverse events): Cross-sectional versus retrospective cohort design 2017 Access copy available to the general public Unrestricted Background Adverse events (AEs) epidemiology is the first step to improve practice in the healthcare system. Usually, the preferred method used to estimate the magnitude of the problem is the retrospective cohort study design, with retrospective reviews of the medical records. However this data collection involves a sophisticated sampling plan, and a process of intensive review of sometimes very heavy and complex medical records. Cross-sectional survey is also a valid and feasible methodology to study AEs. Objectives The aim of this study is to compare AEs detection using two different methodologies: cross-sectional versus retrospective cohort design. Setting Secondary and tertiary hospitals in five countries: Argentina, Colombia, Costa Rica, Mexico and Peru. Participants The IBEAS Study is a cross-sectional survey with a sample size of 11 379 patients. The retrospective cohort study was obtained from a 10% random sample proportional to hospital size from the entire IBEAS Study population. Methods This study compares the 1-day prevalence of the AEs obtained in the IBEAS Study with the incidence obtained through the retrospective cohort study. Results The prevalence of patients with AEs was 10.47% (95% CI 9.90 to 11.03) (1191/11 379), while the cumulative incidence of the retrospective cohort study was 19.76% (95% CI 17.35% to 22.17%) (215/1088). In both studies the highest risk of suffering AEs was seen in Intensive Care Unit (ICU) patients. Comorbid patients and patients with medical devices showed higher risk. Conclusion The retrospective cohort design, although requires more resources, allows to detect more AEs than the cross-sectional design. info:eu-repo/semantics/openAccess by-nc http://creativecommons.org/licenses/by-nc/3.0/es/ 2.413 2017 MEDICINE, GENERAL & INTERNAL 43 / 154 = 0.279 2017 Q2 T1 1.372 2017 Medicine (miscellaneous) 2017 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Limón Ramírez, R. (orcid)0000-0001-9714-8105 Aibar Remón, C. Universidad de Zaragoza Gea-Velázquez De Castro, M.T. Bolúmar, F. Hernández-Aguado, I. López Fresneña, N. Díaz-Agero Pérez, C. Terol García, E. Michel, P. Sousa, P. Larizgoitia Jauregui, I. 1008 615 Universidad de Zaragoza Dpto. Microb.Med.Pr.,Sal.Públ. Área Medic.Prevent.Salud Públ. 7, 10 (2017), e016546 [10 pp] BMJ Open BMJ open 2044-6055 1626564 http://zaguan.unizar.es/record/63192/files/texto_completo.pdf Versión publicada 96622 http://zaguan.unizar.es/record/63192/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:63192 articulos driver 2019-07-09-11:48:10 ARTICLE