000063204 001__ 63204
000063204 005__ 20190709135517.0
000063204 0247_ $$2doi$$a10.2527/jas2017.1736
000063204 0248_ $$2sideral$$a101931
000063204 037__ $$aART-2017-101931
000063204 041__ $$aeng
000063204 100__ $$aDervishi, E.
000063204 245__ $$aMilk yield and genomewide expression profiling in the mammary gland of beef primiparous cows in response to the dietary management during the pre- and postweaning periods
000063204 260__ $$c2017
000063204 5060_ $$aAccess copy available to the general public$$fUnrestricted
000063204 5203_ $$aAccelerated growth programs during prepubertal periods have been promoted to advance the first calving of beef heifers. The objectives of the present study were to evaluate nutrition-induced changes on first lactation milk yield and composition and on gene expression of the mammary gland in Parda de Montaña primiparous cows. Female calves (n = 16) were involved in a 2 × 2 factorial experiment. In the preweaning period (PRE-W; 0–6 mo), female calves were either fed a creep feed supplement (Creep) or fed only their dam’s milk (Control). In the postweaning period (POST-W; 6–15 mo), heifers received either a high-energy diet (91.7 MJ/d) or a moderate-energy diet (79.3 MJ/d). All the heifers were managed together from breeding (15 mo) to the end of their first lactation (32 mo). Animal performance; milk production and quantity during the first lactation; plasma glucose, IGF-I, and leptin concentrations; and RNA samples from the mammary gland at the end of the first lactation of the primiparous cows (32 mo) were analyzed. The BW and ADG of the primiparous cow during its first lactation were not different among treatments; however, creep feeding during PRE-W reduced milk production (P < 0.01), milk CP, crude fat, lactose, nonfat solids, and casein content throughout lactation and increased somatic cell count in the third (P < 0.05) and fourth month of lactation (P < 0.10). The energy level during the POST-W had no effect on milk production and quality. Gene expression in the mammary gland was affected by the diet in the PRE-W and POST-W, with the PRE-W diet having the greatest impact. During the PRE-W, creep feeding resulted in upregulation of genes related to immune response and chemokine activity, suggesting that these animals might be in a compromised immune status. Therefore, this strategy would not be recommendable; meanwhile, increasing the energy level in the diet during the POST-W would be recommendable, because it had no deleterious effects on milk yield and composition.
000063204 536__ $$9info:eu-repo/grantAgreement/ES/INIA/RTA2010-057$$9info:eu-repo/grantAgreement/ES/INIA/RTA2013-059$$9info:eu-repo/grantAgreement/ES/INIA/RZP2012-005
000063204 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000063204 590__ $$a1.711$$b2017
000063204 591__ $$aAGRICULTURE, DAIRY & ANIMAL SCIENCE$$b12 / 59 = 0.203$$c2017$$dQ1$$eT1
000063204 592__ $$a0.848$$b2017
000063204 593__ $$aAnimal Science and Zoology$$c2017$$dQ1
000063204 593__ $$aFood Science$$c2017$$dQ1
000063204 593__ $$aMedicine (miscellaneous)$$c2017$$dQ2
000063204 593__ $$aGenetics$$c2017$$dQ3
000063204 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000063204 700__ $$0(orcid)0000-0003-3875-4935$$aBlanco, M.
000063204 700__ $$aRodríguez-Sánchez, J.A.
000063204 700__ $$0(orcid)0000-0002-8122-0069$$aSanz, A.
000063204 700__ $$aCalvo, J.H.
000063204 700__ $$0(orcid)0000-0003-3943-5311$$aCasasús, I.
000063204 773__ $$g95, 10 (2017), 4274-4287$$pJ. anim. sci.$$tJOURNAL OF ANIMAL SCIENCE$$x0021-8812
000063204 8564_ $$s628970$$uhttps://zaguan.unizar.es/record/63204/files/texto_completo.pdf$$yVersión publicada
000063204 8564_ $$s113177$$uhttps://zaguan.unizar.es/record/63204/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000063204 909CO $$ooai:zaguan.unizar.es:63204$$particulos$$pdriver
000063204 951__ $$a2019-07-09-11:55:56
000063204 980__ $$aARTICLE