New GOLD classification: Longitudinal data on group assignment

Casanova, C.; Marín, M.; Riesco Miranda, J. A.; Agüero, R.; Moreno, A.; Macario, C. C.; Bautista, C. L.; Bonachera, J. C.; Campos, E. M.; Soler-Cataluña, J. J.; Marín Trigo, J. M.; Llunell, A.; Acosta, A. S.; Río, F. G.; Marin, J. M.; de Lucas, P.; Michavila, I. A.; Romero, G. P. -B; Solanes-García, I.; Galdiz, J. B.; Calle-Rubio, M.; de Diego-Damia, A.; Domenech, A.; Irigaray, R.; Márquez Pérez, F. L.; de-Torres, J.; Lobato, S. D.; Balbin, R. A.; Soriano, J. B.; Balcells, E.; Feu-Collado, N.; González, C. M.; Marin, A.; Gómez, R. G.; Soler Cataluña, J. J.; Martinez-Gonzalez, C.; de Lucas-Ramos, P.; Rodríguez, J. T.; López, C. C.; Mir-Viladrich, I.; Alfageme, I.; González, J. A.; de, Miguel D.; Lopez-Campos, J.; Cosio, B.; Piqueras, B. G. -C; Peces-Barba, G.; Marín, J. M.

doi:10.1186/1465-9921-15-3

000063219 001__ 63219
000063219 005__ 20171117104915.0
000063219 0247_ $$2doi$$a10.1186/1465-9921-15-3
000063219 0248_ $$2sideral$$a85221
000063219 037__ $$aART-2014-85221
000063219 041__ $$aeng
000063219 100__ $$aCasanova, C.
000063219 245__ $$aNew GOLD classification: Longitudinal data on group assignment
000063219 260__ $$c2014
000063219 5060_ $$aAccess copy available to the general public$$fUnrestricted
000063219 5203_ $$aRationale: 
Little is known about the longitudinal changes associated with using the 2013 update of the multidimensional GOLD strategy for chronic obstructive pulmonary disease (COPD).
Objective: 
To determine the COPD patient distribution of the new GOLD proposal and evaluate how this classification changes over one year compared with the previous GOLD staging based on spirometry only.
Methods: 
We analyzed data from the CHAIN study, a multicenter observational Spanish cohort of COPD patients who are monitored annually. Categories were defined according to the proposed GOLD: FEV1%, mMRC dyspnea, COPD Assessment Test (CAT), Clinical COPD Questionnaire (CCQ), and exacerbations-hospitalizations. One-year follow-up information was available for all variables except CCQ data.
Results: 
At baseline, 828 stable COPD patients were evaluated. On the basis of mMRC dyspnea versus CAT, the patients were distributed as follows: 38.2% vs. 27.2% in group A, 17.6% vs. 28.3% in group B, 15.8% vs. 12.9% in group C, and 28.4% vs. 31.6% in group D. Information was available for 526 patients at one year: 64.2% of patients remained in the same group but groups C and D show different degrees of variability. The annual progression by group was mainly associated with one-year changes in CAT scores (RR, 1.138; 95%CI: 1.074-1.206) and BODE index values (RR, 2.012; 95%CI: 1.487-2.722).
Conclusions: 
In the new GOLD grading classification, the type of tool used to determine the level of symptoms can substantially alter the group assignment. A change in category after one year was associated with longitudinal changes in the CAT and BODE index.
000063219 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000063219 590__ $$a3.093$$b2014
000063219 591__ $$aRESPIRATORY SYSTEM$$b18 / 57 = 0.316$$c2014$$dQ2$$eT1
000063219 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000063219 700__ $$0(orcid)0000-0001-9096-2294$$aMarin, J. M.$$uUniversidad de Zaragoza
000063219 700__ $$aMartinez-Gonzalez, C.
000063219 700__ $$ade Lucas-Ramos, P.
000063219 700__ $$aMir-Viladrich, I.
000063219 700__ $$aCosio, B.
000063219 700__ $$aPeces-Barba, G.
000063219 700__ $$aCalle-Rubio, M.
000063219 700__ $$aSolanes-García, I.
000063219 700__ $$aAgüero, R.
000063219 700__ $$ade Diego-Damia, A.
000063219 700__ $$aFeu-Collado, N.
000063219 700__ $$aAlfageme, I.
000063219 700__ $$aIrigaray, R.
000063219 700__ $$aBalcells, E.
000063219 700__ $$aLlunell, A.
000063219 700__ $$aGaldiz, J. B.
000063219 700__ $$aMarín, M.
000063219 700__ $$aSoler-Cataluña, J. J.
000063219 700__ $$aLopez-Campos, J.
000063219 700__ $$aSoriano, J. B.
000063219 700__ $$ade-Torres, J.
000063219 700__ $$ade Lucas, P.
000063219 700__ $$aMarín, J. M.
000063219 700__ $$aSoler Cataluña, J. J.
000063219 700__ $$aBonachera, J. C.
000063219 700__ $$aBautista, C. L.
000063219 700__ $$aDomenech, A.
000063219 700__ $$aMichavila, I. A.
000063219 700__ $$aMarín Trigo, J. M.
000063219 700__ $$aGonzález, C. M.
000063219 700__ $$aPiqueras, B. G. -C
000063219 700__ $$aLópez, C. C.
000063219 700__ $$aAcosta, A. S.
000063219 700__ $$aMacario, C. C.
000063219 700__ $$aGonzález, J. A.
000063219 700__ $$aBalbin, R. A.
000063219 700__ $$aCampos, E. M.
000063219 700__ $$aMarin, A.
000063219 700__ $$aMoreno, A.
000063219 700__ $$aMárquez Pérez, F. L.
000063219 700__ $$aRiesco Miranda, J. A.
000063219 700__ $$aRodríguez, J. T.
000063219 700__ $$aGómez, R. G.
000063219 700__ $$aRomero, G. P. -B
000063219 700__ $$ade, Miguel D.
000063219 700__ $$aRío, F. G.
000063219 700__ $$aLobato, S. D.
000063219 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDepartamento de Medicina, Psiquiatría y Dermatología$$cMedicina
000063219 773__ $$g15, 3 (2014),  [9 pp]$$pRespir. res.$$tRESPIRATORY RESEARCH$$x1465-9921
000063219 8564_ $$s762250$$uhttps://zaguan.unizar.es/record/63219/files/texto_completo.pdf$$yVersión publicada
000063219 8564_ $$s107678$$uhttps://zaguan.unizar.es/record/63219/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000063219 909CO $$ooai:zaguan.unizar.es:63219$$particulos$$pdriver
000063219 951__ $$a2017-11-16-11:05:12
000063219 980__ $$aARTICLE

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