63345 20200221144302.0 doi 10.1039/C5CE02526E sideral 101186 ART-2016-101186 eng (orcid)0000-0002-0769-7168 Alegre-Requena, Juan V. Metal-organic frameworks (MOFs) bring new life to hydrogen-bonding organocatalysts in confined spaces 2016 Access copy available to the general public Unrestricted Hydrogen-bonding organocatalysis has emerged as a promising biomimetic alternative to Lewis acid catalysis. Urea, thiourea and squaramide moieties represent the most common hydrogen-bond donors used for the preparation of these catalysts. However, their significant tendency to undergo self-quenching (self-aggregation) often decreases their solubility and reactivity. Recently, scientists have found a promising way around this problem by immobilizing the hydrogen-bonding organocatalysts on metal–organic frameworks (MOFs). Along with advantageous modular synthesis and recycling properties, the tunable porosity and topology of MOFs also allows fast mass transport and/or interactions with substrates. Herein, we highlight the existing examples dealing with the fabrication and testing of hydrogen-bonding organocatalyst-containing MOFs, providing also our vision for further advances in this area. The results derived from these studies will likely serve as inspiration for the future development of superior hydrogen-bonding organocatalysts to accomplish in confined spaces chemical transformations that are either slow or unaffordable under standard homogeneous conditions. info:eu-repo/grantAgreement/ES/CSIC/PIE-201580I010 info:eu-repo/grantAgreement/ES/DGA/E104 info:eu-repo/grantAgreement/ES/UZ/JIUZ-2014-CIE-07 info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 3.474 2016 CRYSTALLOGRAPHY 5 / 26 = 0.192 2016 Q1 T1 CHEMISTRY, MULTIDISCIPLINARY 49 / 166 = 0.295 2016 Q2 T1 1.052 2016 Chemistry (miscellaneous) 2016 Q1 Materials Science (miscellaneous) 2016 Q1 Condensed Matter Physics 2016 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion (orcid)0000-0001-6832-8983 Marqués-López, María Eugenia Universidad de Zaragoza (orcid)0000-0002-5244-9569 Herrera, Raquel P. Universidad de Zaragoza Díaz Díaz, David 2013 765 Universidad de Zaragoza Dpto. Química Orgánica Área Química Orgánica 18, 22 (2016), 3985-3995 CrystEngComm CRYSTENGCOMM 1466-8033 1519744 http://zaguan.unizar.es/record/63345/files/texto_completo.pdf Postprint 123576 http://zaguan.unizar.es/record/63345/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:63345 articulos driver 2020-02-21-13:32:53 ARTICLE