64365 20190930125523.0 doi 10.1080/10255842.2017.1390086 sideral 103126 ART-2017-103126 eng Ramos-Infante, Samuel Jesús Universidad de Zaragoza In vitro and in silico characterization of open-cell structures of trabecular bone 2017 Access copy available to the general public Unrestricted This work aimed to perform a detailed in vitro and in silico characterization of open-cell structures, which resemble trabecular bone, to elucidate osteoporosis failure mechanisms. Experimental and image-based computational methods were used to estimate Young's modulus and porosities of different open-cell structures (Sawbones; Malmö, Sweden). Three different open-cell structures with different porosities were characterized. Additionally, some open-cell structures were scanned using a microcomputed tomography system (µCT) to non-destructively predict specimen Young's modulus of the structures by developing voxel-based and tetrahedral finite element (FE) models. A 3D reconstruction and FE analyses were used. The experimental and computational results with different element types (linear and quadratic tetrahedrons and voxel-based meshes) were compared with Sawbones data (Sawbones; Malmö, Sweden) revealing important differences in Young's modulus and porosities. The specimens with high and low volume fractions were best represented by linear and quadratic tetrahedrons, respectively. These results could be used to develop new osteoporosis-prevention strategies. info:eu-repo/grantAgreement/EUR/FP7/ERC2012-StG-306751 info:eu-repo/grantAgreement/ES/MINECO/DPI2014-53401-C2-1-R info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 1.974 2017 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS 51 / 105 = 0.486 2017 Q2 T2 ENGINEERING, BIOMEDICAL 40 / 78 = 0.513 2017 Q3 T2 0.579 2017 Bioengineering 2017 Q2 Biomedical Engineering 2017 Q2 Medicine (miscellaneous) 2017 Q2 Human-Computer Interaction 2017 Q2 Computer Science Applications 2017 Q2 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion (orcid)0000-0002-2901-4188 Pérez Ansón, María de los Ángeles Universidad de Zaragoza 5004 X Universidad de Zaragoza Dpto. Ingeniería Mecánica Proy. investigacion HJA 5004 605 Universidad de Zaragoza Dpto. Ingeniería Mecánica Área Mec.Med.Cont. y Teor.Est. 20, 14 (2017), 1562-1570 Comput. methods biomech. biomed. eng. Computer methods in biomechanics and biomedical engineering 1025-5842 1687503 http://zaguan.unizar.es/record/64365/files/texto_completo.pdf Versión publicada 115292 http://zaguan.unizar.es/record/64365/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:64365 articulos driver 2019-09-30-12:53:02 ARTICLE