000065589 001__ 65589 000065589 005__ 20200108100347.0 000065589 0247_ $$2doi$$a10.17235/reed.2017.4947/2017 000065589 0248_ $$2sideral$$a104369 000065589 037__ $$aART-2018-104369 000065589 041__ $$aeng 000065589 100__ $$0(orcid)0000-0003-1272-7365$$aSebastián Domingo, Juan José$$uUniversidad de Zaragoza 000065589 245__ $$aFrom the intestinal flora to the microbiome. 000065589 260__ $$c2018 000065589 5060_ $$aAccess copy available to the general public$$fUnrestricted 000065589 5203_ $$aIn this article, the history of the microbiota is reviewed and the related concepts of the microbiota, microbiome, metagenome, pathobiont, dysbiosis, holobiont, phylotype and enterotype are de ned. The most precise and current knowledge about the microbiota is presented and the met- abolic, nutritional and immunomodulatory functions are reviewed. Some gastrointestinal diseases whose pathogen- esis is associated with the intestinal microbiota, including in ammatory bowel disease, irritable bowel syndrome and celiac disease, among others, are brie y discussed. Final- ly, some prominent and promising data with regard to the fecal microbiota transplantation in certain digestive illness are discussed. 000065589 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/ 000065589 590__ $$a1.858$$b2018 000065589 591__ $$aGASTROENTEROLOGY & HEPATOLOGY$$b70 / 84 = 0.833$$c2018$$dQ4$$eT3 000065589 592__ $$a0.524$$b2018 000065589 593__ $$aMedicine (miscellaneous)$$c2018$$dQ2 000065589 593__ $$aGastroenterology$$c2018$$dQ2 000065589 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000065589 700__ $$aSánchez Sánchez, Clara 000065589 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina 000065589 773__ $$g110 (2018), 51-56$$pRev. esp. enferm. dig.$$tRevista española de enfermedades digestivas$$x1130-0108 000065589 8564_ $$s583726$$uhttps://zaguan.unizar.es/record/65589/files/texto_completo.pdf$$yVersión publicada 000065589 8564_ $$s123368$$uhttps://zaguan.unizar.es/record/65589/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000065589 909CO $$ooai:zaguan.unizar.es:65589$$particulos$$pdriver 000065589 951__ $$a2020-01-08-09:31:23 000065589 980__ $$aARTICLE