doi:10.17235/reed.2017.4947/2017engSebastián Domingo, Juan JoséSánchez Sánchez, ClaraFrom the intestinal flora to the microbiome.ART-2018-104369In this article, the history of the microbiota is reviewed and the related concepts of the microbiota, microbiome, metagenome, pathobiont, dysbiosis, holobiont, phylotype and enterotype are de ned. The most precise and current knowledge about the microbiota is presented and the met- abolic, nutritional and immunomodulatory functions are reviewed. Some gastrointestinal diseases whose pathogen- esis is associated with the intestinal microbiota, including in ammatory bowel disease, irritable bowel syndrome and celiac disease, among others, are brie y discussed. Final- ly, some prominent and promising data with regard to the fecal microbiota transplantation in certain digestive illness are discussed.2018http://zaguan.unizar.es/record/6558910.17235/reed.2017.4947/2017http://zaguan.unizar.es/record/65589oai:zaguan.unizar.es:65589Revista española de enfermedades digestivas 110 (2018), 51-56by-nc-ndhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccess