doi:10.1021/acsami.7b17282engRubio-Ruiz, B.Pérez-López, A.M.Bray, T.L.Lee, M.Serrels, A.Prieto, M.Arruebo, M.Carragher, N.O.Sebastián, V.Unciti-Broceta, A.High-Precision Photothermal Ablation Using Biocompatible Palladium Nanoparticles and Laser Scanning MicroscopyART-2018-104607Herein, we report a straightforward method for the scalable preparation of Pd nanoparticles (Pd-NPs) with reduced inherent cytotoxicity and high photothermal conversion capacity. These Pd-NPs are rapidly taken up by cells and able to kill labeled cancer cells upon short exposure to near-infrared (NIR) light. Following cell treatment with Pd-NPs, ablated areas were patterned with high precision by laser scanning microscopy, allowing one to perform cell migration assays with unprecedented accuracy. Using coherent Raman microscopy, cells containing Pd-NPs were simultaneously ablated and imaged. This novel methodology was combined with intravital imaging to mediate microablation of cancerous tissue in tumor xenografts in mice.2018http://zaguan.unizar.es/record/6946310.1021/acsami.7b17282http://zaguan.unizar.es/record/69463oai:zaguan.unizar.es:69463info:eu-repo/grantAgreement/ES/UZ/JIUZ-2016-TEC-13info:eu-repo/grantAgreement/ES/ISCIII/CIBER-BBNinfo:eu-repo/grantAgreement/EC/FP7/614715/EU/A Photo-triggered On-demand Drug Delivery System for Chronic Pain/NANOHEDONISMACS Applied Materials & Interfaces 10, 4 (2018), 3341-3348byhttp://creativecommons.org/licenses/by/3.0/es/info:eu-repo/semantics/openAccess