000070008 001__ 70008 000070008 005__ 20190709135543.0 000070008 0247_ $$2doi$$a10.1159/000446104 000070008 0248_ $$2sideral$$a105168 000070008 037__ $$aART-2017-105168 000070008 041__ $$aeng 000070008 100__ $$aLopez-Valverde, G. 000070008 245__ $$aTherapeutical Management for Ocular Rosacea 000070008 260__ $$c2017 000070008 5060_ $$aAccess copy available to the general public$$fUnrestricted 000070008 5203_ $$aPurpose: The purpose of this study is to describe a case of ocular rosacea with a very complex evolution. Rosacea is a chronic dermatological disease that may affect the ocular structures up to 6-72% of all cases. This form is often misdiagnosed, which may lead to long inflammatory processes with important visual consequences for affected patients. Therefore, an early diagnosis and an adequate treatment are important. Methods: We report the case of a 43-year-old patient who had several relapses of what seemed an episode of acute bacterial conjunctivitis. Two weeks later, he developed a corneal ulcer with a torpid evolution including abundant intrastromal infiltrators and calcium deposits. He was diagnosed with ocular rosacea and treated with systemic doxycycline and topical protopic. Results: A coating with amniotic membrane was placed in order to heal the ulcer, but a deep anterior lamellar keratoplasty to restore the patient''s vision because of the corneal transparency loss was necessary. Conclusions: Ocular rosacea includes multiple ophthalmic manifestations ranging from inflammation of the eyelid margin and blepharitis to serious corneal affectations. A delayed diagnosis can result in chronic inflammatory conditions including keratinization and loss of corneal transparency, which lead to important visual sequelae for affected patients. (C) 2016 The Author(s) Published by S. Karger AG, Basel 000070008 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000070008 592__ $$a0.333$$b2017 000070008 593__ $$aOphthalmology$$c2017$$dQ3 000070008 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000070008 700__ $$0(orcid)0000-0001-6258-2489$$aGarcia-Martin, E.$$uUniversidad de Zaragoza 000070008 700__ $$0(orcid)0000-0002-6745-7668$$aLarrosa-Poves, J.M.$$uUniversidad de Zaragoza 000070008 700__ $$0(orcid)0000-0002-1402-3129$$aPolo-Llorens, V.$$uUniversidad de Zaragoza 000070008 700__ $$0(orcid)0000-0003-2389-8282$$aPablo-Julvez, L.E.$$uUniversidad de Zaragoza 000070008 7102_ $$11004$$2646$$aUniversidad de Zaragoza$$bDpto. Cirugía,Ginecol.Obstetr.$$cÁrea Oftalmología 000070008 773__ $$g7, 1 (2017), 237-242$$pCase rep. ophtalmol.$$tCase reports in ophthalmology$$x1663-2699 000070008 8564_ $$s702343$$uhttps://zaguan.unizar.es/record/70008/files/texto_completo.pdf$$yVersión publicada 000070008 8564_ $$s76612$$uhttps://zaguan.unizar.es/record/70008/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000070008 909CO $$ooai:zaguan.unizar.es:70008$$particulos$$pdriver 000070008 951__ $$a2019-07-09-12:08:17 000070008 980__ $$aARTICLE