000070628 001__ 70628
000070628 005__ 20200221144346.0
000070628 0247_ $$2doi$$a10.7150/jca.12943
000070628 0248_ $$2sideral$$a106007
000070628 037__ $$aART-2016-106007
000070628 041__ $$aeng
000070628 100__ $$aLarrañaga, N.
000070628 245__ $$aIncidence Patterns and Trends of non-Central Nervous System Solid Tumours in Children and Adolescents. A Collaborative Study of the Spanish Population Based Cancer Registries
000070628 260__ $$c2016
000070628 5060_ $$aAccess copy available to the general public$$fUnrestricted
000070628 5203_ $$aObjective: To describe incidence patterns and trends in children (0-14 years) and adolescents (15-19 age-range) with solid tumours, except those of central nervous system (CNS), in Spain. Methods: Cases were drawn from eleven Spanish population-based cancer registries. Incidence was estimated for the period 1983-2007 and trends were evaluated using Joinpoint regression analysis. Results: The studied tumour groups accounted for 36% of total childhood cancers and 47.6% of those diagnosed in adolescence with annual rates per million of 53.5 and 89.3 respectively. In children 0 to 14 years of age, Neuroblastoma (NB) was the commonest (7.8%) followed by Soft-tissue sarcomas (STS) (6.3%), bone tumours (BT) (6.2%) and renal tumours (RT) (4.5%). NB was the most frequently diagnosed tumour before the 5th birthday, while STS and BT were the commonest at 5-9 years of age, and BT and Carcinoma and other epithelial tumours (COET) at 10-14. COET presented the highest incidence in adolescents, followed by germ-cell tumours (GCT), BT and STS. These four diagnostic groups accounted for 94% of total non-CNS solid tumours, in adolescents. Overall incidence rates increased significantly in children up to 1996 with an annual percentage change (APC) of 2.6% (95% CI: 1.7; 3.6). NB and COET showed significant time trend (APCs: 1.4% and 3.8% respectively) while other tumour groups such as RT, STS, BT or GCT had no significant changes over time. A significant increase was present in NB under the age of 5 and in BT and STS in children aged 10-14 years. In adolescents there were significant increases for all tumours combined (APC=2.7; 95% CI: 1.8-3.6) and for STS, GCT and COET (APCs: 3.2%, 4.4% and 3.5% respectively), while other tumour groups such as hepatic tumours, BT or thyroid carcinomas showed a decreasing trend or no increase. Conclusions: Overall, the incidence of the studied cancers in children increased along the period 1983-1996 with no posterior significant rise, while the incidence in adolescents increased significantly over the whole period 1983-2007. Several specific tumour groups showed significant rises or decrements in childhood or adolescence, although the small number of cases precludes showing significant trends or inflexion points.
000070628 536__ $$9info:eu-repo/grantAgreement/ES/FIS/PI-061742
000070628 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000070628 590__ $$a2.916$$b2016
000070628 591__ $$aONCOLOGY$$b113 / 217 = 0.521$$c2016$$dQ3$$eT2
000070628 592__ $$a1.207$$b2016
000070628 593__ $$aOncology$$c2016$$dQ2
000070628 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000070628 700__ $$aSanchez, M.J.
000070628 700__ $$aArdanaz, E.
000070628 700__ $$aFelipe, S.
000070628 700__ $$aMarcos-Gragera, R.
000070628 700__ $$aRamos, M.
000070628 700__ $$aCarulla, M.
000070628 700__ $$aChirlaque, M.D.
000070628 700__ $$aArgüelles, M.V.
000070628 700__ $$aMartos, C.
000070628 700__ $$aMateo, A.
000070628 700__ $$aPeris-Bonet, R.
000070628 773__ $$g7, 3 (2016), 335-343$$pJ. cancer (Wyoming)$$tJournal of cancer (Wyoming, N.S.W.)$$x1837-9664
000070628 8564_ $$s293684$$uhttps://zaguan.unizar.es/record/70628/files/texto_completo.pdf$$yVersión publicada
000070628 8564_ $$s101517$$uhttps://zaguan.unizar.es/record/70628/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000070628 909CO $$ooai:zaguan.unizar.es:70628$$particulos$$pdriver
000070628 951__ $$a2020-02-21-13:52:39
000070628 980__ $$aARTICLE