Guidelines for diagnosis, prevention and management of central nervous system involvement in diffuse large B-cell lymphoma patients by the Spanish Lymphoma Group (GELTAMO)
Peñalver, F.J. ; Sancho, J.M. ; Fuente, Adolfo de la ; Olave, M.T. (Universidad de Zaragoza) ; Martín, A. ; Panizo, C. ; Pérez, E. ; Salar, A. ; Orfao, A.
Resumen: Diffuse large B-cell lymphoma patients have a 5% overall risk of central nervous system events (relapse or progression), which account for high morbidity and frequently fatal outcomes, 1 and shortened overall survival of <6 months.2 Early diagnosis of central nervous system events is critical for successful treatment and improved prognosis. Identification of patients at risk of central nervous system disease is critical to accurately identify candidates for central nervous system prophylaxis vs. therapy.3–5 This report by the Spanish Lymphoma Group (GELTAMO) aims to provide useful guidelines and recommendations for the prevention, diagnosis, and treatment of central nervous system diffuse large B-cell lymphoma patients with, or at risk of, leptomeningeal and/or brain parenchyma lymphoma relapse. A panel of lymphoma experts working on behalf of GELTAMO reviewed all data published on these topics available in PubMed up to May 2016. Recommendations were classified according to the Grading of Recommendations Assessment Development and Evaluation (GRADE) approach.6 A practical algorithm based on the proposed recommendations was then developed (Figure 1). Initial discussions among experts were held in May 2014, and final consensus was reached in June 2016. The final manuscript was reviewed by all authors and the Scientific Committee of GELTAMO.
Idioma: Inglés
DOI: 10.3324/haematol.2016.149120
Año: 2017
Publicado en: Haematologica 102, 2 (2017), 235-245
ISSN: 0390-6078
Factor impacto JCR: 9.09 (2017)
Categ. JCR: HEMATOLOGY rank: 5 / 71 = 0.07 (2017) - Q1 - T1
Factor impacto SCIMAGO: 3.063 - Hematology (Q1)
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes.
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Idioma: Inglés
DOI: 10.3324/haematol.2016.149120
Año: 2017
Publicado en: Haematologica 102, 2 (2017), 235-245
ISSN: 0390-6078
Factor impacto JCR: 9.09 (2017)
Categ. JCR: HEMATOLOGY rank: 5 / 71 = 0.07 (2017) - Q1 - T1
Factor impacto SCIMAGO: 3.063 - Hematology (Q1)
Tipo y forma: Article (Published version)
Área (Departamento): Area Medicina (Dpto. Medicina, Psiqu. y Derm.)
You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. Exportado de SIDERAL (2023-04-21-12:38:52)
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Record created 2018-05-22, last modified 2023-04-21