000071003 001__ 71003
000071003 005__ 20180622124306.0
000071003 0247_ $$2doi$$a10.1557/mrs.2014.224
000071003 0248_ $$2sideral$$a88502
000071003 037__ $$aART-2014-88502
000071003 041__ $$aeng
000071003 100__ $$aGoya, GF
000071003 245__ $$aMagnetic nanoparticles for magnetically guided therapies against neural diseases
000071003 260__ $$c2014
000071003 5060_ $$aAccess copy available to the general public$$fUnrestricted
000071003 5203_ $$aNeurological pathologies and nerve damage are two problems of significant medical and economic impact because of the hurdles of losing nerve functionality in addition to significant mortality and morbidity, and demanding rehabilitation. There are currently a number of examples of how nanotechnology can provide new solutions for biomedical problems. Current strategies for nerve repair rely on the use of functionalized scaffolds working as “nerve guidance channels” to improve axonal regeneration and to direct axonal re-growth across the nerve lesion site. Since low invasiveness and high selectivity of the growth stimulation are usually conflicting requirements, new approaches are being pursued in order to overcome such limitations. Engineered magnetic nanoparticles (MNPs) have emerged from this need for noninvasive therapies for both positioning and guiding neural cells in response to an external magnetic field. Here, we review the current state of the use of MNPs for neuroprotective and magnetically guided therapies. We discuss some conceivable outcomes of current magnetically driven strategies seeking integrated platforms for regenerative action on damaged tissues.
000071003 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000071003 590__ $$a5.667$$b2014
000071003 591__ $$aPHYSICS, APPLIED$$b16 / 141 = 0.113$$c2014$$dQ1$$eT1
000071003 591__ $$aMATERIALS SCIENCE, MULTIDISCIPLINARY$$b28 / 257 = 0.109$$c2014$$dQ1$$eT1
000071003 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000071003 700__ $$0(orcid)0000-0001-9359-0019$$aCalatayud, MP
000071003 700__ $$0(orcid)0000-0002-5578-7635$$aSanz, B
000071003 700__ $$aGiallaccini,M
000071003 700__ $$aRaffa, V
000071003 700__ $$aTorres, TE.
000071003 700__ $$0(orcid)0000-0003-0681-8260$$aIbarra, MR.$$uUniversidad de Zaragoza
000071003 7102_ $$12003$$2395$$aUniversidad de Zaragoza$$bDepartamento de Física de la Materia Condensada$$cFísica de la Materia Condensada
000071003 773__ $$g39, 11 (2014), 965-969$$pMRS bull.$$tMRS BULLETIN$$x0883-7694
000071003 8564_ $$s520891$$uhttps://zaguan.unizar.es/record/71003/files/texto_completo.pdf$$yVersión publicada
000071003 8564_ $$s99588$$uhttps://zaguan.unizar.es/record/71003/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000071003 909CO $$ooai:zaguan.unizar.es:71003$$particulos$$pdriver
000071003 951__ $$a2018-06-22-11:08:14
000071003 980__ $$aARTICLE