75761 20201216081411.0 doi 10.1016/j.phytol.2016.11.005 sideral 97061 ART-2017-97061 eng (orcid)0000-0003-2713-2786 Martín-Ramos, P. Universidad de Zaragoza On the probable composition of ‘Jamaican stone’ aphrodisiac 2017 Access copy available to the general public Unrestricted A dangerous aphrodisiac, commonly known as ‘Jamaican stone’, banned by the U.S. Food and Drug Administration, has been studied by vibrational spectroscopy in order to solve the controversy on its composition. The results of the ATR-FTIR analysis revealed the presence of the a-pyrone ring, which is characteristic of bufadienolides from toad venom and bulbs of squill (Drimia maritima (L.) Stearn). This conclusion was reached after a comparative study with the spectra for phytochemicals derived from gambir and cat''s claw, two Uncaria species also preconized as aphrodisiacs and deemed as possible constituents of the ‘stone’. Owing to their physiologic similarities to digoxin, bufadienolides have been shown to produce a toxic profile similar to that of digoxin, although the lack one of the side chains found on digoxin should allow the use of hemodialysis to treat ‘Jamaican stone’ overdose. info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 1.575 2017 PLANT SCIENCES 95 / 222 = 0.428 2017 Q2 T2 CHEMISTRY, MEDICINAL 48 / 59 = 0.814 2017 Q4 T3 0.634 2017 Agronomy and Crop Science 2017 Q1 Plant Science 2017 Q2 Biotechnology 2017 Q2 Biochemistry 2017 Q3 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Carrión-Prieto, P. Silva-Castro, I. Ruiz-Potosme, N. Hernández-Navarro, S. Martín-Gil, J. 5011 500 Universidad de Zaragoza Dpto. CC.Agrar.y Medio Natural Area Ingeniería Agroforestal 19 (2017), 30-33 Phytochemistry Letters Phytochemistry Letters 1874-3900 151278 http://zaguan.unizar.es/record/75761/files/texto_completo.pdf Postprint 105001 http://zaguan.unizar.es/record/75761/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:75761 articulos driver 2020-12-16-08:09:39 ARTICLE