000076024 001__ 76024
000076024 005__ 20230830110633.0
000076024 0247_ $$2doi$$a10.1016/j.numecd.2016.12.003
000076024 0248_ $$2sideral$$a99046
000076024 037__ $$aART-2017-99046
000076024 041__ $$aeng
000076024 100__ $$0(orcid)0000-0003-2005-8229$$aGonzález-Gil, E.M.$$uUniversidad de Zaragoza
000076024 245__ $$aIdeal cardiovascular health and inflammation in European adolescents: The HELENA study
000076024 260__ $$c2017
000076024 5060_ $$aAccess copy available to the general public$$fUnrestricted
000076024 5203_ $$aBackground and aims
Inflammation plays a key role in atherosclerosis and this process seems to appear in childhood. The ideal cardiovascular health index (ICHI) has been inversely related to atherosclerotic plaque in adults. However, evidence regarding inflammation and ICHI in adolescents is scarce. The aim is to assess the association between ICHI and inflammation in European adolescents.
Methods and results
As many as 543 adolescents (251 boys and 292 girls) from the Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study, a cross-sectional multi-center study including 9 European countries, were measured. C-reactive protein (CRP), complement factors C3 and C4, leptin and white blood cell counts were used to compute an inflammatory score. Multilevel linear models and multilevel logistic regression were used to assess the association between ICHI and inflammation controlling by covariates. Higher ICHI was associated with a lower inflammatory score, as well as with several individual components, both in boys and girls (p < 0.01). In addition, adolescents with at least 4 ideal components of the ICHI had significantly lower inflammatory score and lower levels of the study biomarkers, except CRP. Finally, the multilevel logistic regression showed that for every unit increase in the ICHI, the probability of having an inflammatory profile decreased by 28.1% in girls.
Conclusion
Results from this study suggest that a better ICHI is associated with a lower inflammatory profile already in adolescence. Improving these health behaviors, and health factors included in the ICHI, could play an important role in CVD prevention.
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000076024 590__ $$a3.318$$b2017
000076024 591__ $$aCARDIAC & CARDIOVASCULAR SYSTEMS$$b47 / 128 = 0.367$$c2017$$dQ2$$eT2
000076024 591__ $$aNUTRITION & DIETETICS$$b27 / 79 = 0.342$$c2017$$dQ2$$eT2
000076024 591__ $$aENDOCRINOLOGY & METABOLISM$$b57 / 141 = 0.404$$c2017$$dQ2$$eT2
000076024 592__ $$a1.475$$b2017
000076024 593__ $$aEndocrinology, Diabetes and Metabolism$$c2017$$dQ1
000076024 593__ $$aNutrition and Dietetics$$c2017$$dQ1
000076024 593__ $$aMedicine (miscellaneous)$$c2017$$dQ1
000076024 593__ $$aCardiology and Cardiovascular Medicine$$c2017$$dQ1
000076024 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000076024 700__ $$0(orcid)0000-0002-7297-6104$$aSantabárbara, J.$$uUniversidad de Zaragoza
000076024 700__ $$aRuiz, J.R.
000076024 700__ $$aBel-Serrat, S.
000076024 700__ $$aHuybrechts, I.
000076024 700__ $$aPedrero-Chamizo, R.
000076024 700__ $$ade la O, A.
000076024 700__ $$aGottrand, F.
000076024 700__ $$aKafatos, A.
000076024 700__ $$aWidhalm, K.
000076024 700__ $$aManios, Y.
000076024 700__ $$aMolnar, D.
000076024 700__ $$ade Henauw, S.
000076024 700__ $$aPlada, M.
000076024 700__ $$aFerrari, M.
000076024 700__ $$aPalacios Le Blé, G.
000076024 700__ $$aSiani, A.
000076024 700__ $$aGonzález-Gross, M.
000076024 700__ $$aGómez-Martínez, S.
000076024 700__ $$aMarcos, A.
000076024 700__ $$aMoreno Aznar, L.A.
000076024 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, L.A.$$uUniversidad de Zaragoza
000076024 700__ $$aGottrand, F.
000076024 700__ $$ade Henauw, S.
000076024 700__ $$aGonzález-Gross, M.
000076024 700__ $$aGilbert, C.
000076024 700__ $$aKafatos, A.
000076024 700__ $$aLibersa, C.
000076024 700__ $$aCastelló, S.
000076024 700__ $$aKersting, M.
000076024 700__ $$aSjöstrom, M.
000076024 700__ $$aMolnár, D.
000076024 700__ $$aDallongeville, J.
000076024 700__ $$aHall, G.
000076024 700__ $$aMaes, L.
000076024 700__ $$aScalfi, L.
000076024 700__ $$aMeléndez, P.
000076024 700__ $$aFleta, J.
000076024 700__ $$aCasajús, J.A.
000076024 700__ $$aRodríguez, G.
000076024 700__ $$aTomás, C.
000076024 700__ $$aMesana, M.I.
000076024 700__ $$aVicente-Rodríguez, G.
000076024 700__ $$aVillarroya, A.
000076024 700__ $$aGil, C.M.
000076024 700__ $$aAra, I.
000076024 700__ $$aAlvira, J.F.
000076024 700__ $$aBueno, G.
000076024 700__ $$aLázaro, A.
000076024 700__ $$aBueno, O.
000076024 700__ $$aLeón, J.F.
000076024 700__ $$aGaragorri, J.M.
000076024 700__ $$aBueno, M.
000076024 700__ $$aLabayen, I.
000076024 700__ $$aIglesia, I.
000076024 700__ $$aBel Serrat, S.
000076024 700__ $$aGracia Marco, L.A.
000076024 700__ $$aMouratidou, T.
000076024 700__ $$aSantaliestra-Pasías, A.
000076024 700__ $$aGonzález-Gil, E.M.
000076024 700__ $$ade Miguel-Etayo, P.
000076024 700__ $$aJulián Almárcegui, C.
000076024 700__ $$aMiguel-Berges, M.
000076024 700__ $$aIguacel, I.
000076024 700__ $$aMarcos, A.
000076024 700__ $$aWärnberg, J.
000076024 700__ $$aNova, E.
000076024 700__ $$aGómez, S.
000076024 700__ $$aDíaz, L.E.
000076024 700__ $$aRomeo, J.
000076024 700__ $$aVeses, A.
000076024 700__ $$aZapatera, B.
000076024 700__ $$aPozo, T.
000076024 700__ $$aMartínez, D.
000076024 700__ $$aBeghin, L.
000076024 700__ $$aGottrand, F.
000076024 700__ $$aIliescu, C.
000076024 700__ $$aVon Berlepsch, J.
000076024 700__ $$aSichert-Hellert, W.
000076024 700__ $$aKoeppen, E.
000076024 700__ $$aMolnar, D.
000076024 700__ $$aErhardt, E.
000076024 700__ $$aCsernus, K.
000076024 700__ $$aTörök, K.
000076024 700__ $$aBokor, S.
000076024 700__ $$aAngster.
000076024 700__ $$aNagy, E.Ö.
000076024 700__ $$aKovács, O.
000076024 700__ $$aRépasi, J.
000076024 700__ $$aCodrington, C.
000076024 700__ $$aPlada, M.
000076024 700__ $$aPapadaki, A.
000076024 700__ $$aSarri, K.
000076024 700__ $$aViskadourou, A.
000076024 700__ $$aHatzis, C.
000076024 700__ $$aKiriakakis, M.
000076024 700__ $$aTsibinos, G.
000076024 700__ $$aVardavas, C.
000076024 700__ $$aSbokos, M.
000076024 700__ $$aProtoyeraki, E.
000076024 700__ $$aFasoulaki, M.
000076024 700__ $$aStehle, P.
000076024 700__ $$aPietrzik, K.
000076024 700__ $$aBreidenassel, C.
000076024 700__ $$aSpinneker, A.
000076024 700__ $$aAl-Tahan, J.
000076024 700__ $$aSegoviano, M.
000076024 700__ $$aBerchtold, A.
000076024 700__ $$aBierschbach, C.
000076024 700__ $$aBlatzheim, E.
000076024 700__ $$aSchuch, A.
000076024 700__ $$aPickert, P.
000076024 700__ $$aCastillo, M.J.
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000076024 700__ $$aOrtega, F.B.
000076024 700__ $$aRuiz, J.R.
000076024 700__ $$aArtero, E.G.
000076024 700__ $$aEspaña, V.
000076024 700__ $$aJiménez-Pavón, D.
000076024 700__ $$aChillón, P.
000076024 700__ $$aSánchez-Muñoz, C.
000076024 700__ $$aCuenca, M.
000076024 700__ $$aArcella, D.
000076024 700__ $$aAzzini, E.
000076024 700__ $$aBarrison, E.
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000076024 700__ $$aBuonocore, P.
000076024 700__ $$aCatasta, G.
000076024 700__ $$aCensi, L.
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000076024 700__ $$aD''Acapito, P.
000076024 700__ $$aFerrari, M.
000076024 700__ $$aGalfo, M.
000076024 700__ $$aLe Donne, C.
000076024 700__ $$aLeclercq, C.
000076024 700__ $$aMaiani, G.
000076024 700__ $$aMauro, B.
000076024 700__ $$aMistura, L.
000076024 700__ $$aPasquali, A.
000076024 700__ $$aPiccinelli, R.
000076024 700__ $$aPolito, A.
000076024 700__ $$aRoccaldo, R.
000076024 700__ $$aSpada, R.
000076024 700__ $$aSette, S.
000076024 700__ $$aZaccaria, M.
000076024 700__ $$aVitaglione, P.
000076024 700__ $$aMontagnese, C.
000076024 700__ $$aDe Bourdeaudhuij, I.
000076024 700__ $$aDe Vriendt, T.
000076024 700__ $$aMatthys, C.
000076024 700__ $$aVereecken, C.
000076024 700__ $$ade Maeyer, M.
000076024 700__ $$aOttevaere, C.
000076024 700__ $$aHuybrechts, I.
000076024 700__ $$aWidhalm, K.
000076024 700__ $$aPhillipp, K.
000076024 700__ $$aDietrich, S.
000076024 700__ $$aManios, Y.
000076024 700__ $$aGrammatikaki, E.
000076024 700__ $$aBouloubasi, Z.
000076024 700__ $$aCook, T.L.
000076024 700__ $$aEleutheriou, S.
000076024 700__ $$aConsta, O.
000076024 700__ $$aMoschonis, G.
000076024 700__ $$aKatsaroli, I.
000076024 700__ $$aKraniou, G.
000076024 700__ $$aPapoutsou, S.
000076024 700__ $$aKeke, D.
000076024 700__ $$aPetraki, I.
000076024 700__ $$aBellou, E.
000076024 700__ $$aTanagra, S.
000076024 700__ $$aKallianoti, K.
000076024 700__ $$aArgyropoulou, D.
000076024 700__ $$aTsikrika, S.
000076024 700__ $$aKaraiskos, C.
000076024 700__ $$aMeirhaeghe, A.
000076024 700__ $$aOrtega, F.B.
000076024 700__ $$aHagströmer, M.
000076024 700__ $$aWennlöf, A.H.
000076024 700__ $$aHallström, L.
000076024 700__ $$aPatterson, E.
000076024 700__ $$aKwak, L.
000076024 700__ $$aRizzo, N.
000076024 700__ $$aSánchez-Molero, J.
000076024 700__ $$aPicó, E.
000076024 700__ $$aNavarro, M.
000076024 700__ $$aViadel, B.
000076024 700__ $$aCarreres, J.E.
000076024 700__ $$aMerino, G.
000076024 700__ $$aSanjuán, R.
000076024 700__ $$aLorente, M.
000076024 700__ $$aSánchez, M.J.
000076024 700__ $$aThomas, S.
000076024 700__ $$aAllchurch, E.
000076024 700__ $$aBurgess, P.
000076024 700__ $$aAstrom, A.
000076024 700__ $$aSverkén, A.
000076024 700__ $$aBroberg, A.
000076024 700__ $$aMasson, A.
000076024 700__ $$aLehoux, C.
000076024 700__ $$aBrabant, P.
000076024 700__ $$aPate, P.
000076024 700__ $$aFontaine, L.
000076024 700__ $$aSebok, A.
000076024 700__ $$aKuti, T.
000076024 700__ $$aHegyi, A.
000076024 700__ $$aMaldonado, C.
000076024 700__ $$aLlorente, A.
000076024 700__ $$aGarcía, E.
000076024 700__ $$avon Fircks, H.
000076024 700__ $$aHallberg, M.L.
000076024 700__ $$aMesserer, M.
000076024 700__ $$aLarsson, M.
000076024 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería
000076024 7102_ $$11008$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Med.Pr.,Sal.Públ.$$cÁrea Medic.Prevent.Salud Públ.
000076024 773__ $$g27, 5 (2017), 447-455$$pNMCD, Nutr. Metab. Cardiovasc. Dis.$$tNutrition, Metabolism and Cardiovascular Diseases$$x0939-4753
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000076024 951__ $$a2023-08-30-10:56:54
000076024 980__ $$aARTICLE