000076869 001__ 76869 000076869 005__ 20190118104157.0 000076869 0247_ $$2doi$$a10.3390/bioengineering4040094 000076869 0248_ $$2sideral$$a109437 000076869 037__ $$aART-2017-109437 000076869 041__ $$aeng 000076869 100__ $$0(orcid)0000-0003-2936-242X$$aCatalán Rodríguez, Julia$$uUniversidad de Zaragoza 000076869 245__ $$aSafety Aspects of Bio-Based Nanomaterials 000076869 260__ $$c2017 000076869 5060_ $$aAccess copy available to the general public$$fUnrestricted 000076869 5203_ $$aMoving towards a bio-based and circular economy implies a major focus on the responsible and sustainable utilization of bio-resources. The emergence of nanotechnology has opened multiple possibilities, not only in the existing industrial sectors, but also for completely novel applications of nanoscale bio-materials, the commercial exploitation of which has only begun during the last few years. Bio-based materials are often assumed not to be toxic. However, this pre-assumption is not necessarily true. Here, we provide a short overview on health and environmental aspects associated with bio-based nanomaterials, and on the relevant regulatory requirements. We also discuss testing strategies that may be used for screening purposes at pre-commercial stages. Although the tests presently used to reveal hazards are still evolving, regarding modifications required for nanomaterials, their application is needed before the upscaling or commercialization of bio-based nanomaterials, to ensure the market potential of the nanomaterials is not delayed by uncertainties about safety issues. 000076869 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000076869 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000076869 700__ $$aNorppa, Hannu 000076869 7102_ $$11001$$2420$$aUniversidad de Zaragoza$$bDpto. Anatom.,Embri.Genét.Ani.$$cÁrea Genética 000076869 773__ $$g4 (2017), E94 [8 pp.]$$pBioengineering$$tBioengineering$$x2306-5354 000076869 8564_ $$s207184$$uhttps://zaguan.unizar.es/record/76869/files/texto_completo.pdf$$yVersión publicada 000076869 8564_ $$s102293$$uhttps://zaguan.unizar.es/record/76869/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000076869 909CO $$ooai:zaguan.unizar.es:76869$$particulos$$pdriver 000076869 951__ $$a2019-01-18-09:41:32 000076869 980__ $$aARTICLE