78126 20210208180159.0 doi 10.1016/j.arabjc.2018.01.022 sideral 110633 ART-2019-110633 eng Ortiz, R. Functionalization of p-activated alcohols by trapping carbocations in pure water under smooth conditions 2019 Access copy available to the general public Unrestricted Acetic acid as catalyst in pure water was found to be an excellent reaction medium for the direct dehydrative functionalization of p-activated alcohols using a wide variety of interesting C-, P-, and S-centered nucleophiles, such as indoles, pyrrole, anilines, 1, 3-dicarbonyl compounds, diphenyl phosphite and pyridine-2-thiol. The smooth reaction conditions, along with high yields, short reaction times, clean reaction crudes, an easy product isolation procedure, plus the reusability of the catalyst and the use of no excess of nucleophiles, make this approach an atom economical, green and appealing method to efficiently trap carbocations in pure water, leading to new Csp3 X bonds (X = Csp2, Csp3, P and S). info:eu-repo/grantAgreement/ES/DGA-FSE/E104 info:eu-repo/grantAgreement/ES/DGA-FSE/E77 info:eu-repo/grantAgreement/ES/MINECO/CTQ2017-88091-P info:eu-repo/semantics/openAccess by-nc-nd http://creativecommons.org/licenses/by-nc-nd/3.0/es/ 4.762 2019 0.779 2019 CHEMISTRY, MULTIDISCIPLINARY 45 / 177 = 0.254 2019 Q2 T1 Chemistry (miscellaneous) 2019 Q1 Chemical Engineering (miscellaneous) 2019 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Koukouras, A. (orcid)0000-0001-6832-8983 Marqués-López, E. Universidad de Zaragoza (orcid)0000-0002-5244-9569 Pérez Herrera, R. Universidad de Zaragoza 2013 765 Universidad de Zaragoza Dpto. Química Orgánica Área Química Orgánica 13, 1 (2019), 1866-1873 ARABIAN JOURNAL OF CHEMISTRY ARABIAN JOURNAL OF CHEMISTRY 1878-5352 1155801 http://zaguan.unizar.es/record/78126/files/texto_completo.pdf Versión publicada 91131 http://zaguan.unizar.es/record/78126/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:78126 articulos driver 2021-02-08-17:42:32 ARTICLE