000078172 001__ 78172
000078172 005__ 20200716101441.0
000078172 0247_ $$2doi$$a10.3324/haematol.2018.197152
000078172 0248_ $$2sideral$$a110919
000078172 037__ $$aART-2019-110919
000078172 041__ $$aeng
000078172 100__ $$aPrieto-Torres, L.
000078172 245__ $$aCD30-positive primary cutaneous lymphoproliferative disorders: molecular alterations and targeted therapies
000078172 260__ $$c2019
000078172 5060_ $$aAccess copy available to the general public$$fUnrestricted
000078172 5203_ $$aPrimary cutaneous CD30-positive T-cell lymphoproliferative disorders are the second most common subgroup of cutaneous T-cell lymphomas. They include two clinically different entities with some overlapping features and borderline cases: lymphomatoid papulosis and primary cutaneous anaplastic large cell lymphoma. Molecular studies of primary cutaneous anaplastic large cell lymphoma reveal an increasing level of heterogeneity that is associated with histological and immunophenotypic features of the cases and their response to specific therapies. Here, we review the most significant genetic, epigenetic and molecular alterations described to date in primary cutaneous CD30-positive T-cell lymphoproliferative disorders, and their potential as therapeutic targets.
000078172 536__ $$9info:eu-repo/grantAgreement/ES/MINECO-RTICC-ISCIII-CIBERONC/PIE15-0081$$9info:eu-repo/grantAgreement/ES/MINECO-RTICC-ISCIII-CIBERONC/PI16-01294$$9info:eu-repo/grantAgreement/ES/MINECO-RTICC-ISCIII-CIBERONC/PI17-2172$$9info:eu-repo/grantAgreement/ES/MINECO-RTICC-ISCIII-CIBERONC/RD06-0020-0107-RD012-0036-0060$$9info:eu-repo/grantAgreement/ES/MINECO-RTICC-ISCIII-CIBERONC/SAF2013-47416-R
000078172 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc$$uhttp://creativecommons.org/licenses/by-nc/3.0/es/
000078172 590__ $$a7.116$$b2019
000078172 592__ $$a2.931$$b2019
000078172 591__ $$aHEMATOLOGY$$b7 / 76 = 0.092$$c2019$$dQ1$$eT1
000078172 593__ $$aHematology$$c2019$$dQ1
000078172 655_4 $$ainfo:eu-repo/semantics/review$$vinfo:eu-repo/semantics/publishedVersion
000078172 700__ $$aRodriguez-Pinilla, S.M.
000078172 700__ $$aOnaindia, A.
000078172 700__ $$0(orcid)0000-0001-8789-6783$$aAra, M.$$uUniversidad de Zaragoza
000078172 700__ $$aRequena, L.
000078172 700__ $$aPiris, M.Á.
000078172 7102_ $$11007$$2183$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cÁrea Dermatología
000078172 773__ $$g104, 2 (2019), 226-235$$pHaematologica$$tHaematologica$$x0390-6078
000078172 8564_ $$s522781$$uhttps://zaguan.unizar.es/record/78172/files/texto_completo.pdf$$yVersión publicada
000078172 8564_ $$s112710$$uhttps://zaguan.unizar.es/record/78172/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000078172 909CO $$ooai:zaguan.unizar.es:78172$$particulos$$pdriver
000078172 951__ $$a2020-07-16-08:58:51
000078172 980__ $$aARTICLE