000078317 001__ 78317 000078317 005__ 20230830110635.0 000078317 0247_ $$2doi$$a10.1016/j.nut.2017.10.017 000078317 0248_ $$2sideral$$a105293 000078317 037__ $$aART-2018-105293 000078317 041__ $$aeng 000078317 100__ $$0(orcid)0000-0002-2219-3646$$aIglesia, I. 000078317 245__ $$aDo dietary patterns determine levels of vitamin B6, folate, and vitamin B12 intake and corresponding biomarkers in European adolescents? The Healthy Lifestyle in Europe by Nutrition in Adolescence (HELENA) study 000078317 260__ $$c2018 000078317 5060_ $$aAccess copy available to the general public$$fUnrestricted 000078317 5203_ $$aObjectives: To determine dietary patterns (DPs) and explain the highest variance of vitamin B6, folate, and B12 intake and related concentrations among European adolescents. Methods: A total of 2173 adolescents who participated in the Healthy Lifestyle in Europe by Nutrition in Adolescence study met the eligibility criteria for the vitamin B intake analysis (46% boys) and 586 adolescents for the biomarkers analysis (47% boys). Two non-consecutive, 24-h, dietary recalls were used to assess the mean intakes. Concentrations were measured by chromatography and immunoassay testing. A reduced rank regression was applied to elucidate the combined effect of food intake of vitamin B and related concentrations. Results: The identified DPs (one per vitamin B intake and biomarker and by sex) explained a variability between 34.2% and 23.7% of the vitamin B intake and between 17.2% and 7% of the biomarkers. In the reduced rank regression models, fish, eggs, cheese, whole milk and buttermilk intakes were loaded positively for vitamin B intake in both sexes; however, soft drinks and chocolate were loaded negatively. For the biomarkers, a higher variability was observed in the patterns in terms of food loads such as alcoholic drinks, sugars, and soft drinks. Some food items were loaded differently between intakes and biomarkers such as fish products, which was loaded positively for intakes but negatively for plasma folate in girls. Conclusions: The identified DPs explained up to 34.2% and 17.2% of the variability of the vitamin B intake and plasma concentrations, respectively, in European adolescents. Further studies are needed to elucidate the factors that determine such patterns. 000078317 536__ $$9info:eu-repo/grantAgreement/ES/MICINN-FEDER/JCI-2010-07055$$9info:eu-repo/grantAgreement/ES/MICINN/AGL2007-29784-E$$9info:eu-repo/grantAgreement/ES/ISCIII/RD08-0072-0025$$9info:eu-repo/grantAgreement/EUR/FP6/FOODCT-2005-007034 000078317 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/ 000078317 590__ $$a3.591$$b2018 000078317 591__ $$aNUTRITION & DIETETICS$$b27 / 85 = 0.318$$c2018$$dQ2$$eT1 000078317 592__ $$a1.28$$b2018 000078317 593__ $$aNutrition and Dietetics$$c2018$$dQ1 000078317 593__ $$aEndocrinology, Diabetes and Metabolism$$c2018$$dQ1 000078317 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion 000078317 700__ $$aHuybrechts, I. 000078317 700__ $$0(orcid)0000-0002-3726-1066$$aMouratidou, T. 000078317 700__ $$0(orcid)0000-0002-7297-6104$$aSantabárbara, J.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0002-4145-5103$$aFernández-Alvira, J.M. 000078317 700__ $$0(orcid)0000-0002-0303-7912$$aSantaliestra-Pasías, A.M.$$uUniversidad de Zaragoza 000078317 700__ $$aManios, Y. 000078317 700__ $$aDe la O Puerta, A. 000078317 700__ $$aKafatos, A. 000078317 700__ $$aGottrand, F. 000078317 700__ $$aMarcos, A. 000078317 700__ $$aSette, S. 000078317 700__ $$aPlada, M. 000078317 700__ $$aStehle, P. 000078317 700__ $$aMolnár, D. 000078317 700__ $$aWidhalm, K. 000078317 700__ $$aKersting, M. 000078317 700__ $$aDe Henauw, S. 000078317 700__ $$0(orcid)0000-0003-0454-653X$$aMoreno, L.A.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0003-2005-8229$$aGonzález-Gross, M.$$uUniversidad de Zaragoza 000078317 700__ $$aMoreno, L.A. 000078317 700__ $$0(orcid)0000-0003-1586-1834$$aFleta, J.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0002-7215-6931$$aCasajús, J.A.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0002-7985-9912$$aRodríguez, G.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0002-9240-0778$$aTomás, C.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0001-6836-9101$$aMesana, M.I.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0002-4303-4097$$aVicente-Rodríguez, G.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0002-5139-0630$$aVillarroya, A.$$uUniversidad de Zaragoza 000078317 700__ $$aGil, C.M. 000078317 700__ $$aAra, I. 000078317 700__ $$aAlvira, J.F. 000078317 700__ $$0(orcid)0000-0002-0902-387X$$aBueno, G.$$uUniversidad de Zaragoza 000078317 700__ $$aLázaro, A. 000078317 700__ $$0(orcid)0000-0002-4888-7726$$aBueno, O.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0001-7210-4405$$aLeón, J.F.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0002-5165-9716$$aGaragorri, J.M.A.$$uUniversidad de Zaragoza 000078317 700__ $$aBueno, M. 000078317 700__ $$aLabayen, I. 000078317 700__ $$aIglesia, I. 000078317 700__ $$aBel, S. 000078317 700__ $$aMarco, L.A.G. 000078317 700__ $$aMouratidou, T. 000078317 700__ $$aSantaliestra-Pasías, A. 000078317 700__ $$aIglesia, I. 000078317 700__ $$aGonzález-Gil, E. 000078317 700__ $$0(orcid)0000-0001-6173-5850$$aDe Miguel-Etayo, P. 000078317 700__ $$aAlmárcegui, C.J. 000078317 700__ $$0(orcid)0000-0002-2411-9538$$aMiguel-Berges, M.$$uUniversidad de Zaragoza 000078317 700__ $$0(orcid)0000-0003-4242-5464$$aIguacel, I.$$uUniversidad de Zaragoza 000078317 700__ $$aWärnberg, J. 000078317 700__ $$aNova, E. 000078317 700__ $$aGómez, S. 000078317 700__ $$aDíaz, L.E. 000078317 700__ $$aRomeo, J. 000078317 700__ $$aVeses, A. 000078317 700__ $$aZapatera, B. 000078317 700__ $$aPozo, T. 000078317 700__ $$aMartínez, D. 000078317 700__ $$aBeghin, L. 000078317 700__ $$aLibersa, C. 000078317 700__ $$aGottrand, F. 000078317 700__ $$aIliescu, C. 000078317 700__ $$aVon Berlepsch, J. 000078317 700__ $$aKersting, M. 000078317 700__ $$aSichert-Hellert, W. 000078317 700__ $$aKoeppen, E. 000078317 700__ $$aMolnár, D. 000078317 700__ $$aErhardt, 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$$aHall, G. 000078317 700__ $$aAstrom, A. 000078317 700__ $$aSverkén, A. 000078317 700__ $$aBroberg, A. 000078317 700__ $$aMasson, A. 000078317 700__ $$aLehoux, C. 000078317 700__ $$aBrabant, P. 000078317 700__ $$aPate, P. 000078317 700__ $$aFontaine, L. 000078317 700__ $$aSebok, A. 000078317 700__ $$aKuti, T. 000078317 700__ $$aHegyi, A. 000078317 700__ $$aMaldonado, C. 000078317 700__ $$aLlorente, A. 000078317 700__ $$aGarcía, E. 000078317 700__ $$avon Fircks, H. 000078317 700__ $$aHallberg, M.L. 000078317 700__ $$aMesserer, M. 000078317 700__ $$aLarsson, M. 000078317 700__ $$aFredriksson, H. 000078317 700__ $$aAdamsson, V. 000078317 700__ $$aBörjesson, I. 000078317 7102_ $$11006$$2255$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Enfermería 000078317 7102_ $$11006$$2245$$aUniversidad de Zaragoza$$bDpto. Fisiatría y Enfermería$$cÁrea Educación Física y Depor. 000078317 7102_ $$11008$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Med.Pr.,Sal.Públ.$$cÁrea Medic.Prevent.Salud Públ. 000078317 7102_ $$11010$$2670$$aUniversidad de Zaragoza$$bDpto. Pediatría Radiol.Med.Fís$$cÁrea Pediatría 000078317 773__ $$g50 (2018), 8-17$$pNutrition$$tNUTRITION$$x0899-9007 000078317 8564_ $$s689281$$uhttps://zaguan.unizar.es/record/78317/files/texto_completo.pdf$$yPostprint 000078317 8564_ $$s46979$$uhttps://zaguan.unizar.es/record/78317/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint 000078317 909CO $$ooai:zaguan.unizar.es:78317$$particulos$$pdriver 000078317 951__ $$a2023-08-30-10:57:20 000078317 980__ $$aARTICLE