000078741 001__ 78741
000078741 005__ 20210930085401.0
000078741 0247_ $$2doi$$a10.1039/c7ob02798b
000078741 0248_ $$2sideral$$a104640
000078741 037__ $$aART-2018-104640
000078741 041__ $$aeng
000078741 100__ $$0(orcid)0000-0002-6924-7488$$aCastán, A.
000078741 245__ $$aMichael addition of carbonyl compounds to nitroolefins under the catalysis of new pyrrolidine-based bifunctional organocatalysts
000078741 260__ $$c2018
000078741 5060_ $$aAccess copy available to the general public$$fUnrestricted
000078741 5203_ $$aNovel bifunctional pyrrolidine-based organocatalysts for the asymmetric Michael addition of carbonyl compounds to nitroolefins have been synthesised from homoallylamines, which are easily obtained from (R)-glyceraldehyde as a chiral precursor. Under optimal reaction conditions, these bifunctional organocatalysts showed a high catalytic efficiency (almost quantitative yield in most cases) and stereoselectivity in the Michael addition reactions of a variety of aldehydes (up to 98 : 2 dr and 97% ee) and ketones (up to 98 : 2 dr and 99% ee) to nitroolefins.
000078741 536__ $$9info:eu-repo/grantAgreement/ES/DGA/E102
000078741 540__ $$9info:eu-repo/semantics/openAccess$$aAll rights reserved$$uhttp://www.europeana.eu/rights/rr-f/
000078741 590__ $$a3.49$$b2018
000078741 591__ $$aCHEMISTRY, ORGANIC$$b14 / 57 = 0.246$$c2018$$dQ1$$eT1
000078741 592__ $$a1.119$$b2018
000078741 593__ $$aBiochemistry$$c2018$$dQ1
000078741 593__ $$aPhysical and Theoretical Chemistry$$c2018$$dQ1
000078741 593__ $$aOrganic Chemistry$$c2018$$dQ1
000078741 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000078741 700__ $$0(orcid)0000-0002-5554-3040$$aBadorrey, R.$$uUniversidad de Zaragoza
000078741 700__ $$0(orcid)0000-0002-4972-7476$$aGálvez, J.A.$$uUniversidad de Zaragoza
000078741 700__ $$0(orcid)0000-0001-8105-2432$$aLópez-Ram-De-Víu, P.$$uUniversidad de Zaragoza
000078741 700__ $$0(orcid)0000-0001-9033-8459$$aDíaz-De-Villegas, M.D.
000078741 7102_ $$12013$$2765$$aUniversidad de Zaragoza$$bDpto. Química Orgánica$$cÁrea Química Orgánica
000078741 773__ $$g16, 6 (2018), 924-935$$pOrg. biomol. chem.$$tOrganic & Biomolecular Chemistry$$x1477-0520
000078741 8564_ $$s142434$$uhttps://zaguan.unizar.es/record/78741/files/texto_completo.pdf$$yPostprint
000078741 8564_ $$s66615$$uhttps://zaguan.unizar.es/record/78741/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000078741 909CO $$ooai:zaguan.unizar.es:78741$$particulos$$pdriver
000078741 951__ $$a2021-09-30-08:25:39
000078741 980__ $$aARTICLE