78824 20200716101419.0 doi 10.1038/s41598-019-40341-y sideral 111147 ART-2019-111147 eng (orcid)0000-0002-6116-9331 Torres, T.E. The relevance of Brownian relaxation as power absorption mechanism in Magnetic Hyperthermia 2019 Access copy available to the general public Unrestricted The Linear Response Theory (LRT) is a widely accepted framework to analyze the power absorption of magnetic nanoparticles for magnetic fluid hyperthermia. Its validity is restricted to low applied fields and/or to highly anisotropic magnetic nanoparticles. Here, we present a systematic experimental analysis and numerical calculations of the specific power absorption for highly anisotropic cobalt ferrite (CoFe 2 O 4 ) magnetic nanoparticles with different average sizes and in different viscous media. The predominance of Brownian relaxation as the origin of the magnetic losses in these particles is established, and the changes of the Specific Power Absorption (SPA) with the viscosity of the carrier liquid are consistent with the LRT approximation. The impact of viscosity on SPA is relevant for the design of MNPs to heat the intracellular medium during in vitro and in vivo experiments. The combined numerical and experimental analyses presented here shed light on the underlying mechanisms that make highly anisotropic MNPs unsuitable for magnetic hyperthermia. info:eu-repo/grantAgreement/ES/DGA-FEDER/Construyendo Europa desde Aragón info:eu-repo/grantAgreement/ES/DGA-FEDER/E26 info:eu-repo/grantAgreement/ES/DGA-FEDER/E28-17R info:eu-repo/semantics/openAccess by http://creativecommons.org/licenses/by/3.0/es/ 3.998 2019 1.341 2019 MULTIDISCIPLINARY SCIENCES 17 / 71 = 0.239 2019 Q1 T1 Multidisciplinary 2019 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Lima, E.Jr. (orcid)0000-0001-9359-0019 Calatayud, M.P. (orcid)0000-0002-5578-7635 Sanz, B. Universidad de Zaragoza (orcid)0000-0002-4599-3013 Ibarra, A. Universidad de Zaragoza (orcid)0000-0002-6813-780X Fernández-Pacheco, R. Universidad de Zaragoza Mayoral, A. (orcid)0000-0003-0602-492X Marquina, C. Universidad de Zaragoza (orcid)0000-0003-0681-8260 Ibarra, M.R. Universidad de Zaragoza (orcid)0000-0003-1558-9279 Goya, G.F. Universidad de Zaragoza 2003 395 Universidad de Zaragoza Dpto. Física Materia Condensa. Área Física Materia Condensada 9, 1 (2019), 3992 [11 pp] Sci. rep. Scientific Reports 2045-2322 733525 http://zaguan.unizar.es/record/78824/files/texto_completo.pdf Versión publicada 111407 http://zaguan.unizar.es/record/78824/files/texto_completo.jpg?subformat=icon icon Versión publicada oai:zaguan.unizar.es:78824 articulos driver 2020-07-16-08:38:47 ARTICLE