000079000 001__ 79000
000079000 005__ 20230914083230.0
000079000 0247_ $$2doi$$a10.3390/app9071341
000079000 0248_ $$2sideral$$a111467
000079000 037__ $$aART-2019-111467
000079000 041__ $$aeng
000079000 100__ $$aCatalán-Echeverría, B.
000079000 245__ $$aCFD-based comparison study of a new flow diverting stent and commercially-available ones for the treatment of cerebral aneurysms
000079000 260__ $$c2019
000079000 5060_ $$aAccess copy available to the general public$$fUnrestricted
000079000 5203_ $$aFlow-diverting stents (FDSs) show considerable promise for the treatment of cerebral aneurysms by diverting blood flow away from the aneurysmal sacs, however, post-treatment complications such as failure of occlusion and subarachnoid haemorrhaging remain and vary with the FDS used. Based on computational fluid dynamics (CFD), this study aimed to investigate the performance of a new biodegradable stent as compared to two metallic commercially available FDSs. CFD models were developed for an idealized cerebral artery with a sidewall aneurysmal sac treated by deploying the aforementioned stents of different porosities (90, 80, and 70%) respectively. By using these models, the simulation and analysis were performed, with a focus on comparing the local hemodynamics or the blood flow in the stented arteries as compared to the one without the stent deployment. For the comparison, we computed and compared the flow velocity, wall shear stress (WSS) and pressure distributions, as well as the WSS related indices, all of which are of important parameters for studying the occlusion and potential rupture of the aneurysm. Our results illustrate that the WSS decreases within the aneurysmal sac on the treated arteries, which is more significant for the stents with lower porosity or finer mesh. Our results also show that the maximum WSS near the aneurysmal neck increases regardless of the stents used. In addition, the WSS related indices including the time-average WSS, oscillatory shear index and relative residence time show different distributions, depending on the FDSs. Together, we found that the finer mesh stents provide more flow reduction and smaller region characterized by high oscillatory shear index, while the new stent has a higher relative residence time.
000079000 536__ $$9info:eu-repo/grantAgreement/ES/AEI-MINECO-FEDER/DP12017-83259-R$$9info:eu-repo/grantAgreement/ES/ISCIII/CIBER-BBN$$9info:eu-repo/grantAgreement/ES/MECD/Salvador Madariaga-PRX17-00335
000079000 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/
000079000 590__ $$a2.474$$b2019
000079000 591__ $$aPHYSICS, APPLIED$$b62 / 154 = 0.403$$c2019$$dQ2$$eT2
000079000 591__ $$aENGINEERING, MULTIDISCIPLINARY$$b32 / 91 = 0.352$$c2019$$dQ2$$eT2
000079000 591__ $$aCHEMISTRY, MULTIDISCIPLINARY$$b88 / 176 = 0.5$$c2019$$dQ2$$eT2
000079000 591__ $$aMATERIALS SCIENCE, MULTIDISCIPLINARY$$b161 / 314 = 0.513$$c2019$$dQ3$$eT2
000079000 592__ $$a0.418$$b2019
000079000 593__ $$aEngineering (miscellaneous)$$c2019$$dQ1
000079000 593__ $$aFluid Flow and Transfer Processes$$c2019$$dQ2
000079000 593__ $$aProcess Chemistry and Technology$$c2019$$dQ2
000079000 593__ $$aInstrumentation$$c2019$$dQ2
000079000 593__ $$aMaterials Science (miscellaneous)$$c2019$$dQ2
000079000 593__ $$aComputer Science Applications$$c2019$$dQ3
000079000 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion
000079000 700__ $$aKelly, M.E.
000079000 700__ $$aPeeling, L.
000079000 700__ $$aBergstrom, D.
000079000 700__ $$aChen, X.
000079000 700__ $$0(orcid)0000-0002-0116-2736$$aMalvè, M.
000079000 773__ $$g9, 7 (2019), 1341$$pAppl. sci.$$tApplied Sciences (Switzerland)$$x2076-3417
000079000 8564_ $$s632092$$uhttps://zaguan.unizar.es/record/79000/files/texto_completo.pdf$$yVersión publicada
000079000 8564_ $$s101217$$uhttps://zaguan.unizar.es/record/79000/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada
000079000 909CO $$ooai:zaguan.unizar.es:79000$$particulos$$pdriver
000079000 951__ $$a2023-09-13-10:44:13
000079000 980__ $$aARTICLE