000079092 001__ 79092
000079092 005__ 20201105083208.0
000079092 0247_ $$2doi$$a10.1016/j.atherosclerosis.2018.05.003
000079092 0248_ $$2sideral$$a106403
000079092 037__ $$aART-2018-106403
000079092 041__ $$aeng
000079092 100__ $$aBlasco-Colmenares, E.
000079092 245__ $$aSleep duration and subclinical atherosclerosis: The Aragon Workers' Health Study
000079092 260__ $$c2018
000079092 5060_ $$aAccess copy available to the general public$$fUnrestricted
000079092 5203_ $$aBackground and aims: Few studies have evaluated the association of sleep duration with subclinical atherosclerosis, and with heterogeneous findings. We evaluated the association of sleep duration with the presence of coronary, carotid, and femoral subclinical atherosclerosis in healthy middle-age men with low prevalence of clinical comorbidities.
Methods: We performed a cross-sectional analysis of 1968 men, 40–60 years of age, participating in the Aragon Workers' Health Study (AWHS). Duration of sleep during a typical work week was assessed by questionnaire. Coronary artery calcium scores (CACS) was assessed by computed tomography and the presence of carotid plaque and femoral plaque by ultrasound.
Results: In fully adjusted models, the odds ratios (95% CI) for CACS >0 comparing sleep durations of =5, 6, and =8 h with 7 h were 1.34 (0.98–1.85), 1.35 (1.08–1.69) and 1.21 (0.90–1.62), respectively (p = 0.04). A similar U-shaped association was observed for CACS =100 and for CACS. The corresponding odds ratios for the presence of at least one carotid plaque were =5, 6, and =8 h with 7 h were 1.23 (0.88–1.72), 1.09 (0.86–1.38), and 0.86 (0.63–1.17), respectively (p = 0.31), and for the presence of at least one femoral plaque were 1.25 (0.87–1.80), 1.19 (0.93–1.51) and 1.17 (0.86–1.61), respectively (p = 0.39).
Conclusions: Middle-aged men reporting 7 h of sleep duration had the lowest prevalence of subclinical coronary atherosclerosis as assessed by CACs. Our results support that men with very short or very long sleep durations are at increased risk of atherosclerosis.
000079092 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/IIS16-0114$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI13-02686$$9info:eu-repo/grantAgreement/ES/ISCIII/FIS/PI14-00009
000079092 540__ $$9info:eu-repo/semantics/openAccess$$aby-nc-nd$$uhttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
000079092 590__ $$a4.255$$b2018
000079092 591__ $$aPERIPHERAL VASCULAR DISEASE$$b12 / 65 = 0.185$$c2018$$dQ1$$eT1
000079092 591__ $$aCARDIAC & CARDIOVASCULAR SYSTEMS$$b37 / 136 = 0.272$$c2018$$dQ2$$eT1
000079092 592__ $$a1.748$$b2018
000079092 593__ $$aCardiology and Cardiovascular Medicine$$c2018$$dQ1
000079092 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/acceptedVersion
000079092 700__ $$0(orcid)0000-0003-0604-5042$$aMoreno-Franco, B.$$uUniversidad de Zaragoza
000079092 700__ $$aLeón Latre, M.$$uUniversidad de Zaragoza
000079092 700__ $$aMur-Vispe, E.
000079092 700__ $$0(orcid)0000-0001-8807-9187$$aPocovi, M.$$uUniversidad de Zaragoza
000079092 700__ $$0(orcid)0000-0001-9142-0737$$aJarauta, E.$$uUniversidad de Zaragoza
000079092 700__ $$0(orcid)0000-0001-7043-0952$$aCiveira, F.$$uUniversidad de Zaragoza
000079092 700__ $$0(orcid)0000-0003-3963-0846$$aLaclaustra, M.
000079092 700__ $$0(orcid)0000-0002-9887-2629$$aCasasnovas, J.A.$$uUniversidad de Zaragoza
000079092 700__ $$aGuallar, E.
000079092 7102_ $$11007$$2610$$aUniversidad de Zaragoza$$bDpto. Medicina, Psiqu. y Derm.$$cArea Medicina
000079092 7102_ $$11008$$2615$$aUniversidad de Zaragoza$$bDpto. Microb.Med.Pr.,Sal.Públ.$$cÁrea Medic.Prevent.Salud Públ.
000079092 7102_ $$11002$$2060$$aUniversidad de Zaragoza$$bDpto. Bioq.Biolog.Mol. Celular$$cÁrea Bioquímica y Biolog.Mole.
000079092 773__ $$g274 (2018), 35-40$$pAtherosclerosis$$tAtherosclerosis$$x0021-9150
000079092 8564_ $$s138171$$uhttps://zaguan.unizar.es/record/79092/files/texto_completo.pdf$$yPostprint
000079092 8564_ $$s8029$$uhttps://zaguan.unizar.es/record/79092/files/texto_completo.jpg?subformat=icon$$xicon$$yPostprint
000079092 909CO $$ooai:zaguan.unizar.es:79092$$particulos$$pdriver
000079092 951__ $$a2020-11-05-08:19:50
000079092 980__ $$aARTICLE