79111 20190709135426.0 doi 10.1080/17425247.2016.1205585 sideral 97524 ART-2017-97524 eng Luque-Michel, Edurne Clinical advances of nanocarrier-based cancer therapy and diagnostics 2017 Access copy available to the general public Unrestricted Introduction: Cancer is a leading cause of death worldwide and efficient new strategies are urgently needed to combat its high mortality and morbidity statistics. Fortunately, over the years, nanotechnology has evolved as a frontrunner in the areas of imaging, diagnostics and therapy, giving the possibility of monitoring, evaluating and individualizing cancer treatments in real-time. Areas covered: Polymer-based nanocarriers have been extensively studied to maximize cancer treatment efficacy and minimize the adverse effects of standard therapeutics. Regarding diagnosis, nanomaterials like quantum dots, iron oxide nanoparticles or gold nanoparticles have been developed to provide rapid, sensitive detection of cancer and, therefore, facilitate early treatment and monitoring of the disease. Therefore, multifunctional nanosystems with both imaging and therapy functionalities bring us a step closer to delivering precision/personalized medicine in the cancer setting. Expert opinion: There are multiple barriers for these new nanosystems to enter the clinic, but it is expected that in the near future, nanocarriers, together with new ‘targeted drugs’, could replace our current treatments and cancer could become a nonfatal disease with good recovery rates. Joint efforts between scientists, clinicians, the pharmaceutical industry and legislative bodies are needed to bring to fruition the application of nanosystems in the clinical management of cancer. info:eu-repo/semantics/openAccess All rights reserved http://www.europeana.eu/rights/rr-f/ 5.553 2017 PHARMACOLOGY & PHARMACY 18 / 261 = 0.069 2017 Q1 T1 1.432 2017 Pharmaceutical Science 2017 Q1 info:eu-repo/semantics/article info:eu-repo/semantics/acceptedVersion Imbuluzqueta, Edurne (orcid)0000-0002-6873-5244 Sebastián, Víctor Universidad de Zaragoza Blanco-Prieto, María J. 5005 555 Universidad de Zaragoza Dpto. Ing.Quím.Tecnol.Med.Amb. Área Ingeniería Química 14, 1 (2017), 75-92 Expert Opinion on Drug Delivery Expert Opinion on Drug Delivery 1742-5247 2122836 http://zaguan.unizar.es/record/79111/files/texto_completo.pdf Postprint 12846 http://zaguan.unizar.es/record/79111/files/texto_completo.jpg?subformat=icon icon Postprint oai:zaguan.unizar.es:79111 articulos driver 2019-07-09-11:29:12 ARTICLE