000079688 001__ 79688 000079688 005__ 20210409124034.0 000079688 0247_ $$2doi$$a10.1186/s12888-019-2099-2 000079688 0248_ $$2sideral$$a112462 000079688 037__ $$aART-2019-112462 000079688 041__ $$aeng 000079688 100__ $$0(orcid)0000-0003-4394-5322$$aMira, Adriana$$uUniversidad de Zaragoza 000079688 245__ $$aProtocol for a randomized controlled dismantling study of an internet-based intervention for depressive symptoms: exploring the contribution of behavioral activation and positive psychotherapy strategies 000079688 260__ $$c2019 000079688 5060_ $$aAccess copy available to the general public$$fUnrestricted 000079688 5203_ $$aBackground: there are evidence-based interventions for depression that include different components. However, the efficacy of their therapeutic components is unknown. Another important issue related to depression interventions is that, up to now, their therapeutic components have only focused on reducing negative symptoms rather than on improving positive affect and well-being. Because the low levels of positive affect are more strongly linked to depression than to other emotional disorders, it is important to include this variable as an important treatment target. Positive psychotherapeutic strategies (PPs) could help in this issue. The results obtained so far are consistent and promising, showing that Internet-based interventions are effective in treating depression. However, most of them are also multi-component, and it is important to make progress in investigating what each component contributes to the intervention. Methods: the current study will be a three-armed, simple-blinded, randomized controlled clinical trial with a dismantling design. 192 participants will be randomly assigned to: a) an Internet-based Global Protocol condition, which includes traditional therapeutic components of evidence-based treatments for depression (Motivation for change, Psychoeducation, Cognitive Therapy, Behavioral Activation (BA), Relapse Prevention) and PPs component, offering strategies to enhance positive mood and promote psychological strengths; b) an Internet-based BA Protocol condition (without the PPs component), and c) an Internet-based PPs Protocol condition (without the BA component). Primary outcome measures will be the BDI-II and PANAS. Secondary outcomes will include other variables such as depression, anxiety and stress, quality of life, resilience, and wellbeing related measures. Treatment acceptance and usability will also be measured. Participants will be assessed at pre-, post-treatment, 3-, 6- and 12- month follow- ups. The data will be analyzed based on the Intention-to-treat principle. Per protocol analyses will also be performed. Discussion: to the best of our knowledge, this is the first randomized dismantling intervention study for depression with the aim of exploring the contribution of a PPs component and the BA component in an Internet-based intervention. The three protocols are online interventions, helping to reach many people who need psychological treatments and otherwise would not have access to them. 000079688 536__ $$9info:eu-repo/grantAgreement/ES/ISCIII/CB06-03-0052$$9info:eu-repo/grantAgreement/ES/MINECO/PSI2014-60980-JIN 000079688 540__ $$9info:eu-repo/semantics/openAccess$$aby$$uhttp://creativecommons.org/licenses/by/3.0/es/ 000079688 590__ $$a2.704$$b2019 000079688 592__ $$a1.341$$b2019 000079688 591__ $$aPSYCHIATRY$$b68 / 154 = 0.442$$c2019$$dQ2$$eT2 000079688 593__ $$aPsychiatry and Mental Health$$c2019$$dQ1 000079688 655_4 $$ainfo:eu-repo/semantics/article$$vinfo:eu-repo/semantics/publishedVersion 000079688 700__ $$0(orcid)0000-0003-4398-4014$$aDíaz-García, Amanda 000079688 700__ $$0(orcid)0000-0002-1631-1220$$aCastilla, Diana$$uUniversidad de Zaragoza 000079688 700__ $$aCampos, Daniel 000079688 700__ $$aRomero, Sonia 000079688 700__ $$aBretón-López, Juana 000079688 700__ $$aGarcía-Palacios, Azucena 000079688 700__ $$aBaños, Rosa 000079688 700__ $$aBotella, Cristina 000079688 7102_ $$14009$$2680$$aUniversidad de Zaragoza$$bDpto. Psicología y Sociología$$cÁrea Person.Eval.Trat.Psicoló. 000079688 773__ $$g19 (2019), 133 [13 pp.]$$pBMC Psychiatry$$tBMC Psychiatry$$x1471-244X 000079688 8564_ $$s574040$$uhttps://zaguan.unizar.es/record/79688/files/texto_completo.pdf$$yVersión publicada 000079688 8564_ $$s87703$$uhttps://zaguan.unizar.es/record/79688/files/texto_completo.jpg?subformat=icon$$xicon$$yVersión publicada 000079688 909CO $$ooai:zaguan.unizar.es:79688$$particulos$$pdriver 000079688 951__ $$a2021-04-09-12:36:47 000079688 980__ $$aARTICLE